Sepsis Flashcards

1
Q

What is sepsis?

A

Systemic inflammatory response to infection
Life threatening organ dysfunction caused bacteraemia and dysregulated host response to infection
Medical emergency

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2
Q

Clinical presentation

A
Fever, Rigors, Sweats
Tachycardia
Tachypnoea
Hypotension
Pain, guarding
PR blood
N&V
Diarrhoea
Constipation
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3
Q

Diagnosing sepsis

A
SIRS Criteria 
If you have 2 or more SIRS + infection then you have sepsis
- temperature >38 <36
- heart rate >90 
- resp rate >20
- WCC >12,000 or <4,000
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4
Q

Investigations

A
Bloods - WCC, Platelets, CRP
Cultures - blood, stool, urine
Microscopy - stool, urine, sputum
Serology
PCR
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5
Q

Management

A

Give 3, take 3

  • give high flow O2
  • give IV fluids
  • give IV antibiotics
  • take blood cultures
  • take FBC and lactate (measure of tissue death)
  • take hourly urine output
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6
Q

Antibiotics (emperic formula)

A

Amoxicillin - strep, enterococcus
Metronidazole - anaerobes
Gentamicin - coliforms
Administer for 10-14 days

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7
Q

Septic shock

A

Sepsis induced hypotension

Hallmarks of sepsis + at lease 1 acute organ dysfunction

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