Sepsis Flashcards
1
Q
What is sepsis?
A
Systemic inflammatory response to infection
Life threatening organ dysfunction caused bacteraemia and dysregulated host response to infection
Medical emergency
2
Q
Clinical presentation
A
Fever, Rigors, Sweats Tachycardia Tachypnoea Hypotension Pain, guarding PR blood N&V Diarrhoea Constipation
3
Q
Diagnosing sepsis
A
SIRS Criteria If you have 2 or more SIRS + infection then you have sepsis - temperature >38 <36 - heart rate >90 - resp rate >20 - WCC >12,000 or <4,000
4
Q
Investigations
A
Bloods - WCC, Platelets, CRP Cultures - blood, stool, urine Microscopy - stool, urine, sputum Serology PCR
5
Q
Management
A
Give 3, take 3
- give high flow O2
- give IV fluids
- give IV antibiotics
- take blood cultures
- take FBC and lactate (measure of tissue death)
- take hourly urine output
6
Q
Antibiotics (emperic formula)
A
Amoxicillin - strep, enterococcus
Metronidazole - anaerobes
Gentamicin - coliforms
Administer for 10-14 days
7
Q
Septic shock
A
Sepsis induced hypotension
Hallmarks of sepsis + at lease 1 acute organ dysfunction