Sensory physiology: principles Flashcards

1
Q

efferent nerves/ descending pathways: define

A
  • somatic motor neurons/ autonomic moto neurons

- relay signals form CNS towards an effector (organ, muscle, gland)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

afferent nerves/ ascending pathways: define

A
  • sensory neurons

- relay signals from sensory receptors in PNS towards the CNS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

general visceral afferents:

A
  • provide input to brain about viscera

- processed mostly subconsciously for homeostasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

special visceral afferents:

A
  • nerves that develop in association w GIT and carry info from ‘special senses’ of smell and taste via CN I (olfactory), VII (facial), IX (glossopharyngeal), V (trigeminal), X (Vagus)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

general somatic afferents:

A
  • transmit sensation arising from body surface (touch, pressure)
  • proprioceptive info from mm, joints, skin, inner ear
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

special somatic afferents:

A
  • nerves carry info from special senses vision, hearing, balance via CN II (optic) and VIII (vestibulocochlear)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

sensory transduction: is

A
  • conversion of physical/ chemical stimuli from int/ext environment into neural signals that can effect physiological/ behavioural response
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

sensory transduction: features

A
  • sensory receptors respond to specific modality (energy form)
  • transduce stimulus into form used by nervous system
  • can be simple (mechanical opening of ion channel)
  • transduction process can have amplification stage, esp if transduction is mediated by metabotropic/ G protein coupled receptor (eg. olfactory receptors)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

sensory transduction: pathway

A

stimulus - receptor - transduction - transmission - perception

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

adequate stimulus: modality define

A
  • form of energy particular receptor can respond to
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

adequate stimulus: define

A
  • modality to which particular receptor responds best
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

exteroceptors: are

A

respond to stimuli orginating outside body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

exteroceptors: list

A
  • mechanoreceptors
  • photoreceptors
  • chemoreceptors
  • thermoreceptors
  • magnetoreceptors
  • electroreceptors
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

interoceptors: are

A
  • respond to stimuli originating inside body
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

interoceptors: list

A
  • chemoreceptors (blood O2, CO2, pH)
  • baroreceptors (BP)
  • osmoreceptors (osmotic pressure - fluid balance)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

proprioceptors: are

A

provide info about posture and position of body

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

proprioceptors: list

A

mechanoreceptors

  • proprioception (joint/ limb position)
  • vestibular system (balance/ motion)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

sensory receptor type 1:

A
  • some sensory receptors formed from specialised ending on primary afferent sensory neuron
  • stimulus cause membrane ion channel to open/ close
  • graded potential (generator) -> can initiate AP in same cell
  • depolarising potentials will increase rate of AP generation
19
Q

sensory receptor type 2:

A
  • some sensory receptors are specialised cells separate from primary afferent neuron
  • graded potential generate in receptor cell (non-spiking)
  • voltage gated Ca channels open/ close and increase/ decrease rate of NT release
  • depolarising/ hyperpolarising graded potential is induced in primary afferent neuron -> increase/ decrease rate of firing AP
20
Q

trigger zones:

A
  • multipolar neurons: AP at axon hillock/ initial segment where axon joins soma
  • primary sensory afferent typically psuedounipolar cells -> dendrites (peripheral sensory) and axon terminal (central synaptic end)
  • trigger zone close to receptors/ dendrites (peripheral end)
21
Q

trigger zones: necessary why

A

graded potentials would not be able to travel all the way to soma (in dorsal root ganglion)

22
Q

receptor adaptation: features

A
  • receptors transduce sensory stimuli and respond w graded potentials proportional to stimulus strength and duration
  • some receptors respond w depolarisation of same magnitude for as long as stimulus is applied
  • most receptors reduce magnitude if sustained stimulus
23
Q

receptor adaptation: types

A
  • tonic (slow adapting)

- phasic (rapid adapting)

24
Q

tonic receptors: and eg

A
  • provide continuous updates for long lasting stimulus
  • muscle stretch (prevent over stretch)
  • merkel’s (pressure)
  • nociceptors
25
Q

phasic receptors: and eg

A
  • signal changes in stimulus intensity
  • many respond to cessation of stimulus w off response
  • olfactory receptors
  • touch (pacinian)
26
Q

stimulus intensity: rate (frequency) coding

A
  • larger stimulus - higher magnitude of potential - higher frequency of NT release
27
Q

stimulus intensity: population coding

A
  • stronger stimulus activates more receptors (recruitment)
  • more receptors of same afferent sensory neuron stimulated simultaneously
  • receptors on additional afferent sensory neurons that converge on same area of brain simultaneously
28
Q

stimulus localisation:

A
  • sensory systems organised spatiotopically (touch, vision)

acuity will depend on

  • size of receptive field/ unit
  • density of sensory units (spatial coverage)
  • degree of overlap in receptive fields of adjacent units
  • lateral inhibition
29
Q

define receptive field:

A
  • physical area within which receptors of single sensory unit can detect stimuli
30
Q

overlap of receptive field:

A
  • stimulus falling on overlapping portion of RF of two sensory receptors will stimulate them both neurons simultaneously (population coding)
31
Q

lateral inhibition: features

A
  • increases signal contrast for easy comparison
  • enhance transmission of focal signals, suppress transmission of diffuse signals
  • eg. of presynaptic inhibition
32
Q

lateral inhibition: centre surround RF

A
  • creates functional RF that has:
  • excitatory centre
  • inhibitory surround
33
Q

eg. tactile acuity:

A
  • ability to perceive two points pressed in skin
  • depends on density, RF size, overlap of tactile receptors (mechanoreceptors)
  • meissner’s corpuscles, merkel’s discs involved in fine touch perception and discrimination (small RF)
34
Q

two point discrimination threshold:

A
  • min distance btw points required for tactile discrimination
35
Q

sensory afferent neuronal pathways have two routes:

A
  • part of reflex arc

- relayed upward via ascending pathways -> further processing and possible conscious awareness

36
Q

sensory association areas of cortex:

A
  • identification and interpretation sensory info provided by primary cortical area
  • integration, association (memory) and behaviour
37
Q

define perception:

A
  • awareness and interpretation of sensory info
38
Q

perception: labelled lines

A
  • sensory pathways that transmit info regarding particular modality are specific to that modality
39
Q

Muller’s law (law of specific nerve energies):

A
  • sensation invoked by signals generated in receptor is determined by part of brain that they ultimately activate
40
Q

law of projections:

A
  • regardless of where a particular sensory pathway is stimulated along its course
  • conscious sensation generation is referred to location of receptor
41
Q

law of projections: eg.

A
  • phantom limb pain
  • L arm and chest during heart attack
  • pain signals from visceral pain receptors converge on same spinal neurons as somatic pain receptors
42
Q

inadequate stimulus of sufficient strength may stimulate receptors to respond to inappropriate modalities:

A
  • excessive pressure (mechanical energy) on eye stimulate retinal photoreceptors that normally detect light
  • visual phenomenon (seeing stars)
43
Q

consequences of Muller’s law 2: synaesthesia

A
  • stimulation of one sensory modality eg. vision, evokes perceptual experiences in another, eg. hearing
  • cross talk btw sensory pathways in brain (hearing colours, seeing or smelling sounds, seeing letters as colours)