Sensory Physiology Flashcards

1
Q

What is sensory physiology?

A

How sensory stimuli are transduced by sensory receptors and processed by the nervous system (afferent pathway to CNS)

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2
Q

What is a sensory system?

A

Sense organ + afferent pathway + specific area of brain

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3
Q

What is a sensory receptor?

A

Specialized cell that detects incoming sensory stimuli

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4
Q

What are receptor proteins?

A

Proteins on sensory receptors that detect incoming signals

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5
Q

Epithelial sensory receptor cell

A

Associated to an afferent neuron and relay signals through the release of neurotransmitters

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6
Q

Explain the sequence of signal transduction down a afferent neuron

A

Incoming signals received through dendrites, and action potential is generated at trigger zone (same version as axon hillock) and the AP bypasses the cell body as it travels the length of the axon before reaching the axon terminal and releasing neurotransmitters

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7
Q

What is the basis for sensory receptors classification?

A

The type of stimulus they detect (light, chemicals, etc.)

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8
Q

What are polymodal receptors?

A

Receptors that are sensitive to multiple modalities

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9
Q

What are the 4 steps for sensory reception?

A

1)Reception
2)Transduction
3)Transmission
4)Perception

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10
Q

What is range fractionation?

A

Different sensory receptors that are sensitive to different ranges of stimuli, work together to be able to perceive the intensity

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11
Q

What is the receptive field?

A

Region of sensory surface

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12
Q

What is lateral inhibition?

A

When a stimulus excites a neuron, it will inhibit the neighbouring neurons to release APs to allow for greater specifity to understand the stimulus

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13
Q

Difference between tonic and phasic receptors?

A

Tonic receptors fire APs for the entire duration of the stimulus, where phasic receptors only fire an AP at the initiation of the stimulus

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14
Q

Types of chemoreception

A

Internal & External

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15
Q

Vomeronasal organ

A

Used to capture pheromones

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16
Q

Flehmen response

A

Curving of lip to facilitate the transfer of pheromones to the vomeronasal organ

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17
Q

Gustation

A

Direct contact between chemical @ high concentrations and the animal

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18
Q

Olfaction

A

Airborne chemicals @ lower concentrations interact with animal from a distance

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19
Q

5 categories of taste

A

Umami, sweet, sour, bitter, salty

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20
Q

Which taste’s use G-coupled protein receptors?

A

Umami, sweet and bitter

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21
Q

Which taste’s use ion channel receptors?

A

Salty and sour

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22
Q

What would the body do when having a salt deficiency?

A

Trigger reuptake of aldosterone and that increase the expression of epithelial Na+ channels in the taste buds; inducing a craving

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23
Q

To what taste does the taste map light up and show high neural activity?

A

Bitter tastants

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24
Q

2 systems that are specialized for olfaction?

A

Main olfactory and vomeronasal systems

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25
Explain olfactory reception
Sensory neurons are located in the olfactory epithelium and are directly projected to the olfactory bulb of the brain
26
What is a glomerulus?
A collection of synapses
27
Mechanoreception
Mechanical stimuli that is transduced into electrical signals
28
2 types of mechanoreceptor proteins
ENaCs & TRP channels
29
What are the mechanoreceptors linked to?
The cytoskeleton (intracellularly) and an extracellular anchor (extracellularly)
30
Baroreceptors
Detect pressure changes
31
Tactile receptors
Detect touch, pressure and vibrations on the body
32
Free nerve endings
Sensory neurons with dendrites along the epidermal cells
33
Merkel's Disks
Enlarged epidermal cells that the free nerve endings associate with
34
Ruffini Corpuscle
Dendritic ending with an elongated capsule in the connective tissue
35
Root hair plexus
Nerve endings wrap around base of hair follicle
36
Pacinian Corpuscle
Located deep in the skin; sensitive to vibration and changes in pressure
37
What are the tactile receptors in invertebrates?
Trichoid or campaniform sensilla
38
Proprioception
Encode info about body position
39
Golgi tendon organs
Located at the junction between a muscle and a tendon
40
Chordotonal organ
Detects bending of the cuticle in invertebrates to help understand the animals body position
41
Where are organs of equilibrium and hearing located separately from eachother?
In invertebrates
42
Statoliths
Dense particles of calcium carbonate; that shift depending on orientation which stimulate cilia
43
Which animals have complex statocysts?
Cephalopods; they have cristae (turning motion) and macula (forward motion)
44
Johnston's organ
Modified chordotonal organ
45
What links stereocilia?
Tiplinks; open and close channels
46
Kinocilium
Longest stereocilia; absent in mammals
47
Neuromast organ
Hair cells located in a cupula (filled with viscous gel); when gel shifts, stereocilia bend
48
Lateral line system
Organized neuromasts running the length of body
49
3 parts of the mammalian ear
Outer, middle and inner
50
Parts of the outer ear
Pinna (visible part of the ear) and auditory canal
51
Parts of the middle ear
Ossicles (stapes, malleus & incus) that transfer vibrations from the tympanic membrane
52
Parts of the inner ear
Parts for equilibrium (vestibular apparatus) and hearing (cochlea)
53
Parts of the vestibular apparatus
3 semicircular canals & utricle/saccule
54
Utricle/Saccule
Contain otoliths; utricle detect motion horizontally and saccule detect motion vertically
55
What way do stereocilia bend when depending on direction?
The opposite way (moving forward, stereocilia move backward)
56
Endolymph
Fluid with high K+ concentration
57
Purpose of tympanic membrane
Due to large SA, it concentrates sound vibrations to the oval window
58
2 ducts of the cochlea
Vestibular/tympanic (outside;perilymph) and cochlear (inner;endolymph)
59
Organ of Corti
Space between basilar (vibrate) and tectorial (stable) membranes that contain hair cells
60
Weberian ossicles
Series of bones connecting the swim bladder to the inner ear of a fish
61
Passive electrolocation
Detect fields (electroreceptive)
62
Active electrolocation
Detect and produce fields (electrogenic)
63
Photopigment
Protein + chromophore; determines wavelength color can be seen
64
Types of photoreceptors
Rhabdomeric and ciliary
65
Rhabdomeric photoreceptors
Found only in invertebrates; contain photopigments in microvilli on apical surface
66
Ciliary photoreceptors
Found in both invertebrates and vertebrates; with a single projection from the cell body
67
Rods and cones are what classified by what type of photoreceptors?
Ciliary
68
In what segment of photoreceptors are photopigments located?
Outer
69
Difference in rods and cones
Number of photopigments, dim vs. bright light, response time & retinal position
70
Inner segment of rods/cones
Contains synaptic terminal
71
Opsin
GPCR associated with a chromophore
72
What enzyme reconverts trans to cis conformation of the chromophore?
Isomerase
73
In what species do photoreceptors depolarize in response to light?
Invertebrates
74
Ommatidium
Individual photoreceptor units of a compound eye
75
What is released at the synapse between photoreceptors and bipolar cells?
Glutamate
76
3 types of cones in humans
Blue (short), green (medium), red (long)
77
Visual field
Space detected by retinas of both eyes
78
Binocular zone
Region where left and right visual fields overlap
79
What makes up the optic nerve?
Axons of retinal ganglionic cells
80
Visual cortex
Integrates visual information
81
Lateral Geniculate Nucleus(LGN)
Receives and processes visual information