Self Study 4 - Embryology of the eye Flashcards

1
Q

How does the neural tube form:

A

Ectoderm thickens to form neural plate
Neural crests from from ectoderm
Crests meet forming a hollow tube underneath called the neural tube

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How do the eyes begin to form from the neural tube?

A

The Diencephalic vesicle of the neural tube give off lateral projections called the optic vesicles.

The optic vesicles reach the surface ectoderm which thickens (a placode - thicker embryological area) to form the optic placodes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How are the optic cups formed?

A

The Optic placode invaginates, in turn pushing the optic vesicle to invaginate (forming a two layered optic cup around the placode)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What happens to the optic placode?

A

After it invaginates it seperates from the surface ectoderm becoming the lens vesicle which sits in the optic cup

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How do developing blood vessels reach the optic cup?

A

Through a fissure in its inferior wall called the choroid fissure.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What forms the choroid and sclera?

A

Mesenchyme around the optic cup

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What happens if the choroid fissure fails to close before birth?

A

Part of your eye (e.g. Iris, optic disc or retina) has a key-hole shaped opening called a coloboma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What do the two layers of the optic cup form?

A

Inner layer forms the inner 9 retinal layers
Outer layer forms the 10th retinal layer

This leaves a potential space between the two that can fill with fluid if perforated and cause retinal detachment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What structures ultimately from surface ectoderm?

A
  • Eyelids
  • Conjunctiva
  • Corneal Epithelium
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What structures ultimately form from mesenchyme?

A

Choroid
Stroma of cornea
Sclera
Extraocular muscles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly