Self - antigen and disease Flashcards
1
Q
TSH receptor
A
Hyper/ Hypo thyroid
2
Q
Insulin receptor
A
Hyper/Hypo glycaemia
3
Q
ACH receptor
A
Myasthenia gravis
4
Q
Epidermal cell adhesion molecules
A
Blistering skin diseases
5
Q
Factor VIII
A
Acquired haemophilia
6
Q
Beta-2 glycoprotein and other anticoagulant proteins
A
Antiphospolipid syndrome
7
Q
Red blood cells
A
Haemolytic anaemia
8
Q
Platelets
A
Thrombocytopenic purpura
9
Q
thyroid peroxidase
A
Thyroditis, hypothyroidism
10
Q
Steroid 21- hydroxylase
A
Adddisons disease
11
Q
Glutamate decarboxylase
A
Diabetes 1
12
Q
Lysosomal enzymes (phagocytic cells)
A
Systemic vasculitis
13
Q
Mitochondrial enzymes (particularly pyruvate dyherdrogenase)
A
Primary biliary cirrhosis
14
Q
Double-stranded DNA
A
SLE
15
Q
Histones
A
SLE
16
Q
Topoisomerase I
A
Diffuse scleroderma
17
Q
Amino-acyl-T-RNA synthases
A
Polymyositis
18
Q
Centromere proteins
A
Limited scleroderma
