Hypersensitivity reactions Flashcards
Type 1 onset
Seconds
Type 1 infectious trigger
Schistosomiasis
Type 1 Environment trigger
Allergens
Type 1 autoimmunity
Not applicable
Type 1 adaptive immune system mediators
IgE
Type 1 innate immune system mediators
Mast cells, eosinophils
Type 2 onset
Seconds
Type 2 infectious trigger/ Type 2 Environment trigger/ Type 2 autoimmunity
Immune hemolytic anemias
Type 2 adaptive immune system mediators
IgG/IgM in blood transfusions
Type 2 innate immune system mediators
Complement, phagocytes
Type 3 onset
Hours
Type 3 infectious trigger
Poststreptococcal glomerulonephritis
Type 3 environmental trigger
Farmer’s lung
Type 3 autoimmunity
Systematic lupus erythematous
Type 3 adaptive immune system mediators
IgG
Type 3 Innate immune system mediators
Complement neutrophils
Type 4 onset
2-3 days
Type 4 infectious trigger
Hep B
Type 4 environmental trigger
contact dermatitis
Type 4 autoimmunity
IDDM, celiac, MS, RA
Type 4 adaptive immune system mediators
T cells
Type 4 Innate immune system mediators
Macrophages
