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Antidepressants > Selective Serotonin Reuptake Inhibitors (SSRI) > Flashcards

Selective Serotonin Reuptake Inhibitors (SSRI) Flashcards

1
Q

Examples

A

Sertraline
Fluoxetine
Citalopram

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2
Q

MoA

A

5-HT (serotonin) reuptake transporter
Inhibitor
Prevents reuptake of serotonin into pre-synaptic terminal
Increases duration of action of serotonin at synapse

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3
Q

Indications

A

Depression 1st Line

Panic Disorders

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4
Q

ADR

A 
GI Disturbances
Headache, Agitation, Anxiety
Increased bleeding risk
Hyponatraemia --> elderly common
Sexual dysfunction
NO SEDATION
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5
Q

Prescribing Advice

A

X Other antidepressants
CYP enzyme inhibitor
(QT Prolongation)

Safe in OD
Fluoxetine used in <18

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Antidepressants (5 decks)

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