Noradrenergic + Specific Serotinergic Antidepressants (NaSSAa) Flashcards
1
Q
Example
A
Mirtazapine
2
Q
MoA
A
NA alpha2 auto receptor + heteroreceptors
Antagonist
Reduces alpha2 transmission + enhances release of 5-HT1A-mediated transmission involved in mood regulation
3
Q
Indications
A
Augmentation of Tx for Depression w/ SSRI/SNRI
4
Q
ADR
A
Sedation
Increased appetite + Weight gain
Blood dyscrasia
Cardiac arrhythmias