Noradrenergic + Specific Serotinergic Antidepressants (NaSSAa) Flashcards

1
Q

Example

A

Mirtazapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

MoA

A

NA alpha2 auto receptor + heteroreceptors
Antagonist
Reduces alpha2 transmission + enhances release of 5-HT1A-mediated transmission involved in mood regulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Indications

A

Augmentation of Tx for Depression w/ SSRI/SNRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

ADR

A

Sedation
Increased appetite + Weight gain
Blood dyscrasia
Cardiac arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly