Selective COX-2 Inhibitors Flashcards
1
Q
30 times more potent at inhibiting COX-2 than COX-1
A
Celecoxib
2
Q
Slightly selective for COX-2 than COX-1 enzyme
A
Meloxicam
3
Q
TXA2is formed by …
PGI2 is formed by …
A
COX -1
COX-2
4
Q
Gastric friendly
Lead to renal failure
Higher incidence of cardiovascular thrombotic events
A
Selective COX-2 inhibitors