Selective COX-2 Inhibitors Flashcards

1
Q

30 times more potent at inhibiting COX-2 than COX-1

A

Celecoxib

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2
Q

Slightly selective for COX-2 than COX-1 enzyme

A

Meloxicam

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3
Q

TXA2is formed by …
PGI2 is formed by …

A

COX -1
COX-2

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4
Q

Gastric friendly
Lead to renal failure
Higher incidence of cardiovascular thrombotic events

A

Selective COX-2 inhibitors

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