Selective B-2 until Sympathomimetics Flashcards
Examples of Short Acting Selective B-2 Agonists
Salbutamol
Terbutaline
Examples of Long Acting Selective B-2 Agonists
Formoterol
Salmeterol
Indacaterol
Pirbuterol
Indications of Selective B-2 Agonist
Bronchial Asthma
Used for treatment of asthma exacerbations
SABA (Short Acting Beta-2 Agonists)
Used for prevention of Bronchial Asthma
LABA (Long Acting Beta-2 Agonists)
Examples of Tocolytics
Isoxsuprine
Terbutaline
Ritodrine
Indications for Tocolytics
Premature labor
- labore before 37th week of gestation
Example of Selective D-1 Agonist
Fenoldopam
Indications for Fenoldopam
Alternative in the management of hypertension
Examples of Selective D-2 Agonist
Levodopa
Cabergoline
Bromocriptine
Indication for Levodopa
Parkinson’s Disease
Indication for Cabergoline & Bromocriptine
Hyperprolactinemia
Produced in high concentration in protein-rich foods by decarboxylation of tyrosine during fermentation
Tyramine
How does sympathomimetics work?
stimulate the release of catecholamines from neurons
What is Catecholamine reuptake inhibition
inhibition of catecholamine reuptake which increases concentrations of neurotransmitters ready for receptor binding
Examples of Norepinephrine Reuptake Inhibitors (NARIs)
Reboxetine
Atomexetine
Antidepressants are included here
What does cocaine do?
inhibit dopamine reuptake in the pleasure centers of the brain
What does Monoamine Oxidase Inhibitors (MAOIs) do?
inhibit the enzymes responsible for catecholamine degradation
Indication (depression)
Mechanism of action for Ephedrine & Pseudoephedrine
Agonistic effects on adrenoreceptors
Increase the release of catecholamines
Indications for mixed-acting sympathomimetics
Nasal congestion
Bronchial asthma
Adverse effects of Mixed-Acting sympathomimetics
Tachycardia
Hypertension
Urinary Retention