Seizure Disorders Flashcards
List drugs that are common precipitants of epilepsy
Antibiotics Tramadol Anti-emetics Opioids Aminophylline Amphetamines
What is the mandatory first investigation in all patients presenting with a seizure?
ECG - a seizure could be a sign of a cardiac dysthymia not epilepsy (eg long QT seizure)
Which seizure patients usually qualify for MRI/CT?
Intracranial pathology
Trauma
Focal signs
Low GCS
What is the rule regarding driving after your first seizure?
Can’t drive until seizure-free for:
car: 6 months
hgv: 5 years
What is the rule regarding driving with epilepsy?
Can’t drive until seizure-free for:
car: 1 year
hgv: 10 years
What are the 2 classifications of epileptic seizure?
Focal
Generalised
What is the difference between focal and generalised epileptic seizure?
Focal: part of brain structurally abnormal causing focal symptoms
Generalised: neural cortical pathways conduct seizure to different brain areas
What is the treatment of choice for focal seizures?
Carbamazepine
Lamotrigine/levetiracetam are alternatives
What is the treatment of choice for generalised seizures?
Sodium valproate
Lamotrigine/ethuxosam are alternatives
Which patient group in particular should not be given sodium valproate and why?
Young girls
Teratogenic
Which epileptic drug can make generalised seizures worse?
Carbamazepine
List clinical features of functional non-epileptic attack
Prominent motor activity
Collapse
Fear, gasping, hyperventilation
Prolonged duration (up to 20mins)
What is status epilepticus?
Recurrent epileptic seizures without full recovery of consciousness
List some precipitants of status epilepticus
Infection
Trauma
Metabolic disorders
Withdrawal of anti-convulsants
Which drugs should be administered for acute seizure by carers at home?
Diazepam (rectal)