Segment 3 - Biological Chemistry Flashcards
What is biological chemistry?
The study of chemical reactions and paths of living cells by combining biology and chemistry
What are macromolecules?
Extremely large molecules composed of thousands of atoms
What are the 4 kinds of macromolecules?
Proteins, carbs, lipids, and nucleic acids
What is carbon
The predominant atom in biology and forms the basis of life
What do you call the polymers composed of a-amino acids
Proteins
What is a polymer?
Consists of large molecules
What does the Greek “a” in a-amino acids stand for?
Alpha
An _____ is a molecule with amine and carboxyl functional groups.
Amino acid
What are functional groups?
Specific groupings of atoms within molecules that have their own characteristic properties
How many alpha aminos are there?
20
What is an essential amino acid?
An amino acid that cannot be synthesized by the organism and must be obtained through food
What is a nonessential amino acid?
A naturally produced or occurring amino acid within the body
A ____ chain is what gives each amino acid it’s unique properties.
Side
Glycine is the simplest amino acid. True OR False?
TRUE
What atom is found in the side chain for glycine?
1 hydrogen atom
What are peptides?
Short chains of amino acids
How is a peptide bond formed?
Through a dehydration reaction
When a hydrogen molecule is given up this is called a _____.
Dehydration reaction
What is a polypeptide?
Chains of many acids connected through peptide bonds
_____ in an amino acid in a peptide or polypeptide that remains after a water molecule is removed.
Residue
Peptides have a greater molecular mass than proteins. True OR False?
FALSE. Proteins have a molecular mass of 5,000-40 million
What is the hierarchical system of protein structures in order from least to greatest?
Primary structure, secondary structure, tertiary structure, and quaternary structure
_____ structure is the connection of amino acid residues to form polypeptide chains.
Primary
_____ structure is the 3D shape of a protein largely driven by hydrophobic area of protein within the structure.
Tertiary
____ structure is the arrangement of multiple polypeptide chains to form a larger protein.
Quaternary
______ structure is hydrogen binding between the hydrogen on the nitrogen of one reissued and the carbonyl carbon of another.
Secondary
How is an a-helix formed?
When a peptide chain coils and hydrogen bonds form between them
An a-helix right handed. True OR False
TRUE
What is the structural protein found in human hair and nails?
Beta keratin
What do you call the sheets that bond between amino hydrogens and carbonyl oxygen?
Beta pleated sheets
What is the protein that breaks other protein down into smaller peptides and amino acids for nutrition?
Pepsin
_____ is the process of a protein unfolding from its native structure.
Denaturation
Denaturation can be reversed. True OR False?
FALSE. It is a typically irreversible process
What causes a protein to unfold?
Changes in pH, temp, and salt concentration
What is the protein that catalyzes reactions?
An enzyme
A catalyst speeds up reactions by _______ activation energy of the reaction.
Lowering