Sedative Hypnotics Flashcards

1
Q

Types of Sedative Hypnotics

A

Benzodiazepines (diazepam, flurazepam)
Barbiturates (phenobarbital, secobarbital)
Other agents (ethanol, chloral hydrate)
Over-the-counter agents (antihistamines)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are major points in the graded depression of the reticular activating system (arousal/sleep-awake cycle)?

A
Low dose 
-anti-anxiety
-sedation
-hypnosis
-anesthesia
High dose
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

When were barbiturates first synthesized?

A

1864

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

When were benzodiazepines first synthesized?

A

1930

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Points of administration/absorption

A
  • produces CNS depression
  • readily absorbed from digestive tract
  • different preparations available with different lipid solubilities
  • highly lipid soluble
How well did you know this?
1
Not at all
2
3
4
5
Perfectly