Sedation & GA Flashcards

1
Q
  1. What is the definition of conscious sedation?
A
  • A technique un which the use of drugs or drugs produces a state of depression of the CNS enabling tx to be carried out but during which verbal contact wiht the patient is maintained throughout.
  • The level of sediation means that the patient remains conscious, retains protective reflexes and is able to understand and respond to verbal commands

The drugs and techniques sued to provide conscious sedation for dental treatment should carry a margin of safety wide enough to render unintended loss of consciousness unlikely

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2
Q

What is GABA?

A

Gamma-aminobutyric acid

Gamma-aminobutyric acid (GABA) is a neurotransmitter, a chemical messenger in your brain. It slows down your brain by blocking specific signals in your central nervous system (your brain and spinal cord). GABA is known for producing a calming effect.

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3
Q

What is GABAs function?

A

Has a calming affect
- Inhibitory neurotransmitter in the CNS
- It acts to inhibit nerve transmission in the brain calming the nervous activity
- (Benzodiazepines act on receptors in the CNS to enhance the effects of GABA in the cerebel cortec and motor ciruits this inhibiting CNS neurotransmitters producing a sedative effect.

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4
Q

What are the indications for inhalation sedation?

A
  • Medical conditions which are aggrevated by stress. Epilepsy, hypertension, asthma
  • Dental. Unpleasant or traumatic procedures
  • Social. Dental phobia, high levels of dental anxiety or prominent gag reflex
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5
Q
  1. What are the contraindications for inhalation sedation?
A
  • Severe or uncontrolled medical conditions, mental or physcial disability or psychiatric problems
  • Unable to nose breath. Blocked nasal airway, common cold/flu, tonsillitis, poor co-operation to nose or mouth breath(must be able to co-ordinate nasal breathing with mouth open open hard for children)
  • Narcolepsy, Hypoparathyroidism or pregnancy (espically 1st trimester)
  • Severe COPD
  • Unwilling and unco-operative
  • Dental procedure too difficult for LA alone
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6
Q

What are the indications for intravenous sediation?

A
  • As for inhalation sediation plus also useful for patient prone to fainting
  • Conditions with poor co-operation such as mild to moderate movement or learning difficulties (spacisty disorder e.g cerebral palsy or Parkinson’s disease.
  • N.B Doesnt work so well for gagging patients
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7
Q

What are the contraindications for IV sediation?

A
  • Severe or uncontrolled medical conditions, mental or physcial disabilities or psychiatric problems
  • Severe COPD
  • Extremes of age <12
  • Unaccompanied patients
  • If procedure is too long for IV sediation >50mins
  • Unwilling or unco-operative patients
  • Dental procedure too difficult fro LA alone
  • Certain medications erythromycin
  • Intracranial pathology - likely already being monitored using AVPU and sediation with further decrease alterness, skew AVPU results and make monitorign the patient difficult
  • Myasthenia gravis
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8
Q
  1. What are the safety features of the (quantiflex) machine present when giving inhalation sedation?
A
  • Oxygen flush button
  • Reservoir bag
  • Minimum oxygen 30%
  • Air entrainment valve
  • Different coloured cylinders - black for oxygen and blue for NO2 so cant get mixed up and can only be attached one way.
  • Nitrous oxide stops when oxygen stops
  • Oxygen monitor built in - fail safe at 40psi
  • One wat expiratory valve
  • Pressure reducing valves
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9
Q
  1. What are the advantages of using inhalation sedation over IV midazolam?
A
  • Quicker onset 2-3minutes and peak action 3-5 minutes
  • Rapid recovery
  • Can increase and decrease the degree of sedation
  • NO2 is not metabolised so safer than midazolam
  • Less post-operative effects
  • No needles or cannulas (issue for patients scared of needles)
  • No amnesia
  • Adult patients dont require a chaperone
  • Can be used on children under the age of 12
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10
Q

What is the half life of midazolam?

A

90-150 minutes

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11
Q

GIve 6 things you assess a patient before IV sedation?

A
  • Heart rate
  • Oxygen saturation
  • Blood presssure
  • Height and weight for BMI
  • ASA classification
  • MH and Drug history
  • Co-operation level
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12
Q

What is the ASA classification?

A

American society of anaesthesiologists
Is a way of classifying how fit and well a patient is. It can be used to determine what treatment is possible, using what techniques and in what setting. Including with sedation.

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13
Q

What are all of the ASA classifications and give an example for each?

A

Class l - normal healthy patient
class ll - mild systemic disease. eg well controlled asthma and epilepsy, type 2 diabetes, pregancy, borderline hypertension.
Class lll - Severe systemic disease. Eg stable angina, COPD, Type 1 diabetes, Hisotry of MI (more than 3 months)
Class lV - Severe systemic disease that is a constant threat to life e.g severe COPD and unstable angina, recent MI or stroke (less than 3 months). Marked hypertension
Class V - A moribound patinet who is not expected to survive without the operation.
Class Vl - Declared brain dead patient whos organs are being removed for donor purposes

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14
Q

What do you monitor in a sedated patient and what time intervals

A
  • Heart rate
  • Blood pressure
  • oxygen saturation
  • Monitor every 5 minutes
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15
Q

Patient is having his lower left 3rd molar removed under IV sedation.
1. Why is written consent gained prior to the sedation process?

A
  • Legal requirement that written consent is obtained where concious sedation is to be used
  • Consent process starts at a seperate appointment prior to tx unles there is exceptional circumstances (e.g acute pain) which allows the patient sufficent time to consider the information provided
  • The consent should also be reconfirmed at least verbally on the day of the procedure
  • Consent is gained prior to the sedation process as once the patient has been administered with the sedative they no longer have the capacity to consent
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16
Q

As a UK dentist, what drug is commonly used for IV sedation and what preparation is it?

A

Midazolam
1mg/ml or 5mg/5ml
Patient intially given 2mg bolus and then titrated extra 1mg every 60s until the level of ideal sedation is reached.

17
Q

Name 3 vital signs you would monitor before, during and after sedation?

A

HR
BP
Oxygen saturation

18
Q

What drug is used to reverse the effects of midazolam?

A

Flumazenil

19
Q

Give 3 pieces of advice you would give the patinet after sedation?

A
  • Must have a chaperone fro next 24hrs
  • No operating heavy machinery for rest of the day
  • No driving for 24hrs
  • No excercise for 24hrs
  • Stay of social media, emailing and banking as decision making is impaired
  • No involvements in signing of legal documents
20
Q

General Anaesthetic-
1. Why might a referral for general anaesthetic be made?

A
  • Generally. Child too anxious or young
  • Where benefits of GA outway the risks
  • Patient unco-operative phobic or severely anxious
  • For children requireing complete or comprehesive tx (full clearance)
  • For un-coperative under 12s or special needs children
  • Extensive, complex or long treatment
  • CLP

Child needs to be asleep for treatment because they are too young, anxious or unco-operative to accept tx any other wat or the dentist needs patient to be guaranteed to be completely still as operation is complex

21
Q
  1. What are the stages of anaesthesia?
A
  • Induction
  • Excitement
  • Surgical anaesthesia (stage you are aiming for)
  • Respiratory paralysis or overdose
22
Q
  1. What needs to be included in a referral letter for GA?
A
  • Patient details (DOB name address)
  • If child then guardian details
  • Who has parental resposibility
  • GMP and GDP contact details (Should be informed going for GA)
  • MH, any conditions, drugs, allergies
  • DH
  • justification for GA referral
  • Radiographs for backing up justification
  • proposed tx plan for during GA
  • Previous tx details
23
Q

Local Anaesthetic-
1. How does local anaesthetics work?

A

LA works by blocking the voltage gated osdium channels which prevents the rising phase of nerve action potential and so AP generation and propagation and nerve firing (action persists so long as sufficent sodium channels are blocked and the AP isnt achieved)

24
Q

What nerve fibres are more susceptible to LA?

A

A delta fibres and C fibres

  • Ay (main fibres responsible for nociception- pain) and C (less voltage gates sodium channel per unit) then AB, Aa
25
Q
  1. Name 1 ester and 3 amide anaesthetics?
A

Ester - Benzocaine
Amine - Lignocaine, prilocaine and articaine

26
Q
  1. What is in a cartridge of local anaesthetic?
A
  • Ester or amide base is present as base hydrochloride
  • Reducing agent - sodium metabisulphite (stabilises LA for a prolonged period
  • Preservative - methylparaben (reduce risk of contamination when in cart
  • Fungicide
  • Vasoconstrictor +/-
27
Q
  1. What is the maximum dose of lignocaine?
A

5mg per kg

28
Q
  1. What is the distribution of different types of LA- infiltration and block?
A
  • Infiltration- deposited around the terminal branches of nerves
  • Block- deposited beside the nerve trunk
29
Q
  1. What are the three components of LA?
A
  • Aromatic region- hydrophobic (allows diffusion)
  • Ester or amide bond
  • Basic amid side chain- hydrophilic (allows dilution of LA in syringe)
30
Q

Inferior Alveolar Block-
1. What are the landmarks for an IAN block?

A
  • Coronoid notch of mandibular ramus- thumb placed here intra-orally
  • Posterior border of the mandible- fingers placed here extra-orally to support the jaw
  • Pterygomandibular space and raphe
  • Lower premolar teeth of the opposite side
  • Aiming for deposition in the region of (slightly above) the mandibular foramen
  • Advance needles over the opposing premolars and inject 6-10mm up from the occlusal table into the buccal fat pad- ¾ of the way from the coronoid process (thumb- lateral to injection site) to the pterygomandibular raphe (medial to injection site) (this is the pterygomadibular space)
  • Advance to bony contact withdraw slightly, aspirate and inject
31
Q
  1. Name 2 alternative techniques?
A
  • Akinosi technique
  • Gow-gates technique
32
Q
  1. How do you manage a patient if you accidently inject into the parotid gland?
A
  • Explain the situation to the patient and apologise
  • Give them assurance that any symptoms will eb temporary and there is no permanent damage
  • Provide eye protection in the form of an eye patch until the blink reflex returns to normal
  • Advise the patient that the length of paralysis can vary but will improve over a period of weeks
  • Review the patient
33
Q

Maximum Doses-
List the Maximum Doses for the Following Anaesthetic Agents-
1. Lidocaine 2% W/ 1: 80,000 adrenaline

A
  • Max dose- 5mg/kg (kids 4.4mg/kg)
  • Max dose of adrenaline- 500µg

  1. Articaine 4% W/ 1: 100,000 adrenaline
    * Max dose- 7mg/kg (kids 5mg/kg)