sedation drugs Flashcards
def of conscious sedation
the reduction or abolition of the phycological & physiological responses to the stress of dentistry without he loss of consciousness, cooperation for protective reflexes
routes of drug administration
iv -certain absorption/action terminated by redistribution,metablosm and excretion)
inhalation- rapid absorption and rapid elimination
oral- gastric absorption or slow onset
benzodiazepines modes of action
mainly on the limbic system
BZD act on receptors in the CNS to enhance the effect of GABA by inhibiting its re-uptake. GABA inhibits neurotransmission. GABA is on the cerebral cortex and motor circuit and ban are close to GABA receptors
benzodiazepines also mimic glycerin which is a inhibitory neurotransmitter in the spina cord
benzodiazepines clinical effect
anxioulysis - reduced fear sedation detachment- 2-30mins amnesia muscle relaxant disinhibition- we don't do it on under 16 as can get violent anticonvulsant anaesthesia NOT ANALGESICS -MAY INFLUENCE RESPONSE TO PAIN
Diazepam
can burn when entering in due to solvents.
long half life so lasts for several days