Section 5: Vascular Physiology Flashcards
Blood flow equation
Flow = Change in pressure over resistance
resistance equation
R = 8ηL/πr^4
where η is vicosity
L is length
r is radius
Viscosity of blood is determined by
amount of RBC by volume
Regulated by haemocrit
Pulse pressure
difference between systolic and diastolic
Mean arterial pressure
diastolic pressure + pulse pressure/3
Closer to diastolic b/c heart spends more time relaxing
Cardiac output (flow) in relation to pressure
F=MAP/R
where MAP is mean arterial pressure
factors that influence vasodilation
myogenic activity oxygen carbon dioxide pH endothelin sympathetic influence vasopressin angiotensenII temperature histamine NO
Baroreceptor reflex
autonomic mediation of heart veins and arterioles to adjust in the short term
Adjusts blood volume through urine and salt over long period
Primary hypertension
catch-all term for high BP associated with specific disease
secondary hypertension
occurs due to a known problem (10% of cases)
causes of secondary hypertension
renal, endocrine, neruogenic
4 types of shock
hypovolemic
cardiogenic
vasogenic (sepsis or anaphylaxis)
neurogenic