Section 3 Flashcards
Anatomy and Neurosurgery
Enkephalins are the main neurotransmitters from
A. Cerebral cortex to caudate
B. Subthalamic nucleus to caudate
C. Caudate to putamen
D. Putamen to globus pallldus extemus
E. Thalamus to cerebral cortex
D. Putamen to globus pallldus extemus
GABA and enkephalins are the main neurotransmitters from putamen to globus pallidus extemus (GPe), GABA and substance P from GPe to globus pallidus internus (GPi), GABA from caudate to SN, GPe to STN, and GPi to thalamus. Ach is
the main neurotransmitter from cerebral cortex to caudate, caudate to putamen, and lateral amygdala to cortex. Glutamate is the main neurotransmitter from cerebral cortex to putamen and STN, STN to GPe, GPi, and SN, thalamus to cortex and putamen. Dopamine is the main neurotransmitter from SN pars compacta to striatum, serotonin and cholecystokinin from dorsal raphe nucleus (DRN) to SN, serotonin and enkephalins from DRN to caudate.
Which thalamic nucleus receives mostly input from the cerebellum. and has output to the motor cortex?
A. VA (ventral anterior)
B. VLo (ventral lateral, pars oralis) (Voa: ventralis oralis anterior]
C. VLc (ventral lateral, pars caudalis) (Vop: ventralis oralis posterior and Vim: ventralis intermediate nucleus]
D. MD (medial dorsal)
E. LP (lateral posterior)
C. VLc (ventral lateral, pars caudalis) (Vop: ventralis oralis posterior and Vim: ventralis intermediate nucleus]
VLc (Vop and Vim) and VPLo receive input from dentate nucleus of the cerebellum and project to motor area 4, VA and VLo (Voa) receive input from GP and project to premotor cortex, MD from prefrontal cortex, temporal cortex, amygdala, SN, and GP and project to prefrontal cortex. LP receives input and projects to area 5.
With basilar tip aneurysm surgery, the highest risk of perforating vessel injury occurs when the aneurysm is directed
A. Anteriorly
B. Posteriorly
C. Cranially
D. To the right
E. To the left
B. Posteriorly
Basilar tip aneurysms pointing posteriorly carry the highest risk of perforator injury during clipping. Basilar tip aneurysms are now best treated endovascularly with coiling or stent-coiling.
Wartenberg’s sign is associated with which nerve injury?
A. Ulnar n
B. Median n
C. Radial n
D. Common peroneal n
E. Tibial n
A. Ulnar n
Wartenberg’s sign consists of inability to adduct the little finger due to weakness of interossei secondary to ulnar n palsy. The little finger is abducted due to the unopposed action of extensor digiti mini mi.
In the following diagram, the vein of Galen is labeled
A. 1
B. 2
C. 4
D. 5
E. 7
C. 4
- Inferior sagittal sinus; 2. straight sinus; 3. internal cerebral v; 4. vein of Galen; 5. basal v of Rosenthal; 6. thalamostriate v; 7. transverse sinus; 8. superior sagittal sinus.
In the same diagram, the Internal cerebral v is labeled
A. 1
B. 3
C. 4
D. 5
E. 6
B. 3
- Inferior sagittal sinus; 2. straight sinus; 3. internal cerebral v; 4. vein of Galen; 5. basal v of Rosenthal; 6. thalamostriate v; 7. transverse sinus; 8. superior sagittal sinus.
In the following figure, Ammon’s horn is number
A. 1
B. 2
C. 3
D. 4
E. 7
B. 2
- Dentate gyrus; 2. Cornu Ammonis (hippocampus); 3. subiculum; 4. entorhinal cortex; 5. optic tract; 6. temporal horn of lateral ventricle; 7. fimbria of fomix; 8. tail of caudate nucleus; 9. alveus; 10. choroid plexus.
In the same diagram. the dentate gyrus is number
A. 1
B. 2
C. 3
D. 4
E. 5
B. 2
- Dentate gyrus; 2. Cornu Ammonis (hippocampus); 3. subiculum; 4. entorhinal cortex; 5. optic tract; 6. temporal horn of lateral ventricle; 7. fimbria of fomix; 8. tail of caudate nucleus; 9. alveus; 10. choroid plexus.
During an endoscopic third ventriculostomy, the opening in the Door of the third ventricle should be made
A. Anterior to 3
B. Through 3
C. Through 1
D. Through 2
E. Posterior to 2
C. Through 1
An endoscopic third ventriculostomy is done through the membrane (1) between the Mammillary bodies (2) and the Median eminence; through the latter the pituitary infundibulum passes. The membrane (1) is part of the tuber cinereum.
In the figure above, the infundibular recess is
A. Anterior to 3
B. 3
C. 1
D. 2
E. Posterior to 2
B. 3
- infundibular recess.
The main neurotransmitter from the subthalamic nucleus to the globus pallidus is
A. Glutamate
B. Acetylcholine
C. Dopamine
D. Serotonin
E. GABA (Gamma Amino Butyric Acid)
A. Glutamate
Glutamate is the main neurotransmitter from STN to GPe, GPi, and SN.
The medial dorsal nudew of thalamus (MD) projects to the
A. Prefrontal cortex
B. Area 4
C. Areas 3, 1, and 2
D. Parietal association area
E. Banks of the calcarine sulcus
A. Prefrontal cortex
MD from prefrontal cortex, temporal cortex, amygdala, SN, and GP and project to prefrontal cortex.
In the following view of the foramen of Monro, the fornix is located at
A. 1
B. 2
C. 3
D. 4
E. None of the above
A. 1
In this endoscopic view of the right lateral ventricle, the fornix (1) forms the superior and anterior boundary of the foramen of Monro (4). The choroid plexus is observed between the septum pellucidum (3) and thalamus (2).
The corticospinal tract occupies which part of the internal capsule?
A. Anterior limb
B. Genu
C. Anterior part of the posterior limb
D. Posterior part of the posterior limb
E. Sublenticular part
D. Posterior part of the posterior limb
The corticospinal fibers occupy the posterior half of the posterior limb of the internal capsule with the legs represented posteriorly, corticobulbar the genu, auditory projections in sublenticular (inferior thalamic peduncle), visual in retrolenticular (posterior thalamic peduncle). The anterior limb contains the anterior thalamic peduncle, while the posterior limb contains the superior thalamic peduncle.
In the cerebellar architecture, all of the following structures are inhibitory, except
A. Basket cells
B. Outer stellate cells
C. Purkinje cells
D. Pyramidal cells
E. Granule cells
E. Granule cells
Excitatory structures in the cerebellum include: climbing fibers, mossy fibers, and granule cells. All other cells are inhibitory.
The risk of stroke from > 70 % symptomatic carotid a stenosis at 2 years is
A. 5 %
B. 9 %
C. 11%
D. 26 %
B. 70 %
D. 26 %
Based on NASCET, carotid endarterectomy reduces the risk of stroke from 26% to 9% over 2 years in symptomatic patients with 70-99% stenosis.
The annual rate of rupture of intracranial aneurysms is
A. 0,5 %
B. 1-2 %
C. 2-4 %
D. 6 %
E. 20 %
C. 2-4 %
The annual risk of rupture of cavernomas is 0.5-1%, aneurysms 1-2%, AVMs 2-4%. After AVM rupture: mortality 10%, morbidity 30%, rebleed 6% in the first 6 months. After aneurysm rupture, prehospital death is 50%, of the remaining patients there is 20% mortality, 20% morbidity, rebleed 50% in 6 months worst in the first 24 hours.
The meningohypophyseal trunk is a branch of which segment of the ICA?
A. Petrous
B. Cavernous
C. Clinoidal
D. Ophthalmic
E. Communicating
B. Cavernous
The cavernous carotid a gives the McConnell’s capsular a, the inferior cavernous a, and the meningohypophyseal trunk. The meningohypophyseal trunk gives the dorsal meningeal a, inferior hypophyseal a, and the tentorial artery of Bernasconi and Cassinari. The petrous carotid gives off vidian, caroticotympanic, and occasionally stapedial aa. The ophthalmic segment: ophthalmic and superior hypophyseal aa, the communicating segment: posterior communicating and anterior choroidal aa.
The normal cerebral blood flow is
A. <8 mL/100 g/min
B. 8-23 mL/100 g/min
C. 50 mL/100 g/min
D. 75 mL/100 g/min
E. >75 mL/100 g/min
C. 50 ml/100 g/min
The normal cerebral blood flow is 50 mL/100 g/min, with higher flow in the gray matter than the white matter. In the ischemic penumbra, it is 8-23 mL/100 g/min. The normal Oxygen consumption is 3,5 mL/100 g/min.
Which circumventricular organ is paired and enduces emesis?
A. Subforniceal organ
B. Subcommissural organ
C. Organum vasculosum
D. Area postrema
D. Area postrema
The circumventricular organs are devoid of BBB except the subcommissural organ. The subfornical organ and organum vasculosum detect serum osmolarity. The area postrema is the only paired organ and it induces emesis.
The cerebrospinal fluid (CSF) is normally produced at a rate of
A. 150 mL/d
B. 300 mL/d
C. 450 mL/d
D. 600 mL/d
E. 750 mL/d
C. 450 ml/d
The normal adult CSF volume is 150 mL, of which 30 mL intraventricular, 40 mL spinal subarachnoid space, and 80 mL cranial subarachnoid space. The body produces 3 times the CSF volume per day ( 450 mL).
The superior hypophyseal a is a branch of which segment of the ICA?
A. Petrous
B. Cavernous
C. Clinoidal
D. Ophthalmic
E. Communicating
D. Ophthalmic
Branches of the ophthalmic segment of ICA: ophthalmic and superior hypophyseal aa.
The anterior choroidal a supplies all of the following, except
A. Optic tract
B. Internal capsule
C. Thalamus
D. Red nucleus
E. None of the above
E. None of the above
The anterior choroidal a is a branch of the communicating segment of the ICA, has cisternal and plexal segments, and supplies internal capsule, optic chiasm, optic tract, optic radiation, thalamus, GP, cerebral peduncle, SN, red nucleus, and choroid plexus of lateral ventricle.
Which artery, when present, is a branch of the Pl segment of the PCA and supplies the thalamus and midbrain bilaterally?
A. Percheron
B. Benasconi and Cassinari
C. Adamkiewicz
D. Calcarine
E. Medial posterior choroidal
A. Percheron
The a of Percheron is a variant unpaired branch of the PCA supplying thalamus and midbrain bilaterally. Occlusion causes bilateral thalamic infarcts.