Section 20: Antibiotic Control Of Microorganisms Flashcards
Antibiotic
Chemical agents safe for use internally for patient care
Alexander Fleming
Biologists who discovered penicillin
Narrow-spectrum Antibiotic
Target specific type of bacteria
Broad-spectrum Antibiotic
Inhibit or kill many/all bacteria
Selective Toxicity
Ability to target the microbes with no effect on the patient
Penicillin
Cell wall
Cidal
None in 90% of people, 10% are allergic
Vancomycin
Cell wall
Cidal
Very toxic—use only when necessary
Polymyxin
Cytoplasmic membrane
Cidal
Neohrotoxic
Aminoglycosides
Protein synthesis
Cidal
Deafness
Tetracycline
Protein synthesis
Static
Grating of developing teeth
Chloramphenicol
Protein synthesis
Static
Depresses the immune system
Rifampin
RNA synthesis
Static
Hepatitis
Sulfa Drugs
Inhibit the synthesis of the vitamin folic acid
How to reduce spread of antibiotic resistance?
1) reduce antibiotics used in animal feed
2) not giving unnecessary antibiotics
3) treat with sufficient concentration and time
Kirby-Bauer Test
1) drugs for which the given microbe is sensitive
2) concentration level at which drug is effective