Section 15: Genes, Gene Replication, And Gene Therapy Flashcards
Diploid
Eukaryotes that have two copies of each chromosome
Gene
DNA coding sequence with upstream control sequences for a single protein
Haploid
Prokaryotes that contain one copy of chromosome
Frederick Griffith
He showed that capsular production could be restored to a capsular mutant from dead, wild-type bacteria
Oswald Avery
Showed that the bacterial substance that caused transformation was DNase sensitive, providing strong evidence that transferral of DNA rather than protein or RNA was necessary for capsule production
Alfred Hershey and Martha Chase Experiment
Confirm that DNA, rather than protein, is the genetic material
DNA Replication
Produces to double-stranded DNA molecules identical to the starting DNA
DNA Proofreading
Test to see if the newly added nucleotides are complementary to the template. If they are not complementary, DNA polymerase removes and replaces them with a new nucleotide
Gene Therapy
Treatment of disease by introducing wild-type genes into a human or other organism that may lack them
Wild-Type Bacterium
Bacterium lacking mutations
All genes functioning normally
Has a capsule
Mutant
Defective gene