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T3- GIGU unit1 > secretion > Flashcards

secretion Flashcards

1
Q

Gastrin is released from ___ cells in the ___ and ___

A

G cells

in the antrum and duod

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2
Q

Gastrin is stim by (3)

A
  1. protein digestion
  2. Nervous , physical distention
  3. Ca+2, decaf coffee , and wine
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3
Q

G-17 is gastrin released from the ____

A

antrum

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4
Q

G-34 is gastrin released from the ___

A

duod

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5
Q

trophic activity of gastrin does what?

A

stim growth of oxyntic mucosa of stomach, duod mucosa, and colon mucosa

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6
Q

c.c name the gastrinoma condition

A

zollinger- ellison sx

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7
Q

c.c. location of a zollinger- ellison sx gastrinoma

A

non beta cell tumor of pancreas or g cell in duod

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8
Q

c.c. sx of a zollinger ellison sx gastrinoma

A

diarrhea
duod ulcer
steatorrhea
hypokalemia

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9
Q

location of CCK release

A

I cells in duod & jejunum

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10
Q

CCK secretion is stim by (3)

A
  1. FA/ monoglycerides (not triglycerides)
  2. Peptides & AA
  3. Acid
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11
Q

Physio effects of CCK on the pancreas and stomach

A

GB: contracts GB relaxes sphincter of Oddi

inhibits : inhibits gastric emptying

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12
Q

CCK has trophic effects on ___ & ____ mucosa

A

pancreas and GB

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13
Q

location of Secretin secretion

A

S cells of the duod

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14
Q

Secretin release is stim by (2)

A

acid in duod

FA in duod

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15
Q

Location of GLIP secretion

A

duod & prox jejunum

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16
Q

what (4) factors stim GLIP

A

fat
acid
carbs
oral glucose

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17
Q

what horm will stim the release of insulin

A

GLIP

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18
Q

What horm is released during fasting

A

motilin

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19
Q

_____ horm accounts for the migrating motility complex “housekeeping contractions”

A

motilin

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20
Q

What is the only GI horm secreted in the antrum

A

gastrin

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21
Q

What are the only 2 GI horm that are secreted in the Ileum

A

CCK

secretin

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22
Q

All GI horm are ___

A

peptides

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23
Q

___ & ___ strongly stim secretion of acid in parietal cells

A

histamine

gastrin

24
Q

______ are stomach cells that secrete gastric acid (HCl) and intrinsic factor.

A

parietal cells

acted upon by histamine and gastrin

25
Q

_____ receptor blockers decrease acid secretion

A

Histamine H2 receptor blockers

Names: Cimetidine & ranitidine

26
Q

source of VIP

A

Gut mucosa and SM

27
Q

Name the (3) NT of the GI tract

A

VIP
GRP
Enkephalin

28
Q

Fxn of the VIP NT

A

relaxation of gut SM
relaxes LES

(aka: vasoactive intestinal peptide)

29
Q

FXn of GRP (bombesin)

A

increase gastrin release

aka: gastrin- releasing peptide

30
Q

Location of Enkephalin NT secretion

A

Gut mucosa and SM

31
Q

action of enkephalin NT

A

increase SM tone

32
Q

Which GI organ secretes very acidic secretions

A

stomach

pH : 2

33
Q

Which GI organ secretes very basic secretions for neutralization

A

pancreas

pH: 8

34
Q

Which GI organs (3) secrete neutral secretions

35
Q

the daily vol of GI secretions is ___Liters

36
Q

(4) mech of stim of secretion in the GI tract

A
  1. mech presence of food
  2. activiation of enteric NS : tactile, chem, distention of gut
  3. Autonomic stim
  4. hormonal
37
Q

What are (3) mech to activate the enteric NS

A
  1. tactile stim
  2. chem irritation
    distention of gut wall
38
Q

oral cavity saliva is secreted by 3 major glands

A

parotid (serous)
submandivular (mixed)
sublingual (mucous)
(buccal glands)

39
Q

parotid is a ___ gland

40
Q

submandibular is a __ gland

A

mixed

- provides 69% of oral cavity secretion

41
Q

Which oral cavity gland contributes the most to saliva

A

submandibular

42
Q

Sublingual is a ___ gland

43
Q

______ digests starch in the oral cavity

A

alpha amylase

44
Q

c.c. ______viral infection of the parotid gland

45
Q

what are the 6 constituents of saliva

A 
mucus 
ptyalin (a-amylase) 
lingual lipase
kallikrein 
NaHCO3
water
46
Q

What saliva constitute forms bradykinin

A

kallikrein

vasodilator

47
Q

_____ increases pH for optimum fxn of amylase

48
Q

____ protein allows for lubrication in the oral cavity

49
Q

______protein is an antibacterial protein in the oral cavity

50
Q

_____ acts as a Ca+ binding protein in the oral cavity

A

proline rich proteins

51
Q

increa. flow in the salivary duct increa. ____ conc bc it can not be absorbed fast enough

52
Q

saliva is ____. It becomes less conc. in Na+ and Cl- bc of absorption

53
Q

____ ion moves out of the cell with Na+

54
Q

what two cranial Nerves help the PS system to increase flow rate of saliva

A

facial

glossopharyngeal

55
Q

what two N control the taste reflex

A

facial (submandibular gg) –> subman and subling

glossopharngeal (otic gg) –> parotid

56
Q

_____ blocks the muscarenic AcH receptors so AcH cant bind to make saliva

57
Q

NE bind to ___ receptors to activate cAMP to secrete enzymes

A

beta adrenergic receptors

T3- GIGU unit1 (4 decks)

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