Secondary Hemostasis

Question 1

The process of secondary hemostasis

Answer 1

Coagulation > Fibrin Clot formation > Fibrin Stabilization

Question 2

4 Categories of Plasma-based Components of the Coagulation System of Blood clotting:

Answer 2

1. Zymogen
2. Cofactors
3. Control proteins
4. Fibrinogen Substrate

Question 3

Inactive form of enzymes also known as procoagulants

Answer 3

Zymogens

Question 4

Example of zymogens (8)

Answer 4

• Pre-Kallikrein
• FXII
• FXI
• FIX
• FX
• FVII
• Prothrombin
• FXIII

Question 5

Binds (to zymogen in their activated form), stabilized and enhance activity of their respective enzymes

Answer 5

Cofactors

Question 6

Examples of Cofactors (7)

Answer 6

• HMWK
• Tissue factor
• FVIII
• FV
• Protein Z
• Protein S
• Thrombomodulin

Question 7

Serve the important functions of regulating the coagulation process to avoid unnecessary blood clotting

Answer 7

Control proteins

Question 8

Fibrinogen is the substrate for the enzymatic action of thrombin, the primary enzyme of the coagulation system  destroying of clot

Answer 8

Fibrinogen Substrate

Question 8

Fibrinogen is the substrate for the enzymatic action of thrombin, the primary enzyme of the coagulation system  destroying of clot

Answer 8

Fibrinogen Substrate

Question 9

The year when the international committee for the standardization of the nomenclature of the blood clotting factors officially named the plasma procoagulants using roman numerals in the order of their initial description or discovery

Answer 9

1958