SECOND PRIORITY (3) Flashcards

1
Q

surra is transmitted by hematophagous flies called:

A

stomoxys and tabanus

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2
Q

CA of surra

A

t. evansi, congolense, brucei, vivax

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3
Q

trypanosomiasis pathogenesis

__ into skin via insect bite

Localized swellings

Infect __

Rapid division in the bloodstream

____– attach to endothelial cells
_____ - invade tissues and
cause damage

A

Tryopanosomes into skin via insect bite

Localized swellings

Infect LN

Rapid division in the bloodstream

*T. congolense – attach to endothelial cells
*T. brucei and T. vivax - invade tissues and
cause damage

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4
Q

T. evansi infections of cattle and buffalo usually
lead to pronounced

A

immunosuppression

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5
Q

ausative agent of leptospirosis

A

l. interrogans

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6
Q

earned its name from a characteristic hooked appearance that resembles a question mark

A

leptospirosis

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7
Q

t/f all serovars of Leptospira are pathogenic, and many are associated with a reservoir species in which little disease is apparent.

A

f

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8
Q

many serovars are highly prevalent within maintenance host populations and persist in the ___ and ___

A

kidneys or genital tract.

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9
Q

high antibody responses and low tissue burdens are typical in these animals. with lepto

A

low abs

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10
Q

leptospira is resistant to dessication T/F

A

freezing, dehydration, and UV radiation inactivate leptospires

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11
Q

majority of leptospira serovars have specific maintenance hosts

A

t

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12
Q

Leptospira serovars known to cause disease in mammals have been isolated from __

A

amphibians

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13
Q

3rd most impt dx in indonesia

A

surra

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14
Q

dz that can be inoculated in mice for lab dx

A

surra

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15
Q

pH preference of leptospira

A

neutral to slight alkalaine

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16
Q

all are serovars of canids except

a. bratislava
b. canicola
c. icterohemorrhagiae
d. pomona
e. hardjo
f. grippotyphosa

A

none

17
Q

lepto can be transmitted venerally or tranplacentally

A

t. but not all serovars

18
Q

encourages persistence of lepto in the environment.

A

rainfall

19
Q

Maintenance hosts typically do not develop significant clinical disease

A

tr

20
Q

develops rapidly and is a significant contributor to mortality in lepto infected animals

A

Acute renal injury

21
Q

hosts that develop reproductive disease acutely (lepto)

A

incidental hosts

22
Q

incidental hosts for lepto remain subclinical for weeks to months t.f

A

f. maintenance

23
Q

Best available method to determine infecting serovar of lepto

A

bacterial culture

24
Q

Does not provide serovar-specific results

A

PCR

25
Q

standard serological test for diagnosing leptospirosis,

A

MAT

26
Q

In experienced hands, the _ of leptospires is one of the most specific methods of demonstrating
their presence,

A

isolation

27
Q

agar used for culure of lepto

A

Bismuth sulphite agar

28
Q

Addition of 0.4–5% ___ to semisolid culture medium enhances the chances of isolating fastidious
leptospiral serovars

A

rabbit serum

29
Q

less fastidious serovars of lepto

A

Pomona and Grippotyphosa

30
Q

are increasingly used for the detection of leptospires in
tissues and body fluids of animals because of their perceived sensitivity and capacity to give an early
diagnosis.

A

PCR

31
Q

Subsequent differentiation to the
serovar level was traditionally by __, although for most isolates this is now being done using less time-consuming methods such as monoclonal antibodies (MAbs).

A

cross-agglutination absorption

32
Q

is the laboratory procedure most frequently used to confirm the clinical diagnosis, to determine
herd prevalence, and to conduct epidemiological studies

A

serology testing

33
Q

uses live antigens is the most widely used serological test

A

MAT