SECOND PRIO (2) Flashcards
brucellosis affecting cattle
b. abortus
brucella sp. affecting goats
b. melitensis
brucella species affecting sheep
b. ovis
principal manifestation of brucellosis
reproductive failure in males and females
other term for brucellosis
Undulant fever, Mediterranean fever, Abortus fever, Contagious abortion, Bang’s Disease, Malta fever
brucellosis in cattle causes abortion in what phase of pregnancy
last 3 months
other animal susceptible to brucellosis
dogs
brucellosis organism has greatest numbers in what organs
pregnant uterus, fetus, fetal membranes
disease with a risk of spread from AI
brucellosis
risk factor of bang’s dz
proximity to infected herds = double fence
causes undulant fever
brucellosis
Brucellosis pathogenesis
Bacteria causes ___ ↓
Multiplies in the ___
↓
Invades ____, _, __ ___ ↓
Bacteremia for months
↓
Pregnant: ulceration of the ____ then cotyledon and villi
↓
Abortions, still birth, weak calves
Bacteria causes lymphadenitis ↓
Multiplies in the phagocytes
↓
Invades spleen, LN, mammary gland, uterus ↓
Bacteremia for months
↓
Pregnant: ulceration of the endometrium then cotyledon and villi
↓
Abortions, still birth, weak calves
brucellosis is Characterized by __ followed by
localization of infection in the _ and __
septicemia
lymph node and
genital organ
where do brucella replicates?
phagocytes
brucella sp. causes ulceration of the ___, __ and __in pregnants
endometrium
then cotyledon and villi
substance normally produced by the fetus
stimulates growth of Brucella sp
erythritol
T.F erythritol is directly proportional to stage of pregnancy at time of ingestion
inversely
brucellosis induces abortion after __ mos
5
brucella can cause -___on the knees , stifles, hock etc
Hygromas
-edematous placenta
-presence of leathery plaques on the chorion’s
external surface
-necrosis of the cotyledons
brucellosis
t/f trying to
control B. melitensis in sheep and goats is much
more difficult
T
safer technique if want to salvage genetic material from infected animal)
embryo transfer
human manifestation of brucellosis
undulant fever
in brucellosis, Those who recovered can still breed but are considered _ of the dz
reservoirs
large scale screening of sera of brucella from buffaloes/carabaos is done thru
rose bengal test
Principle of rose bengal test: serum has Ab against brucella =__
agglutination
source of infection of b.ovis in major sheep-producing regions
infected ram
Passive venereal infection is when infection from ram is passed via ___
female reproductive tract
b. melitensis effect on humans
mediterranean fever or malta
brucella that has high risk of bioterorrism
b. melitensis
b. melitensis is first observed in_
maltese sheep
cells attacked by b. abortus
PMNs (NEB), MO, DCs
*Vaccination program that target cattle against ___ have proved effective but trying to control ___ in sheep and goats is much more difficult
B. abortus
B. melitensis
tx for b. ovis
oxytet, dihydrostreptomycin
fasciola infecting in cooler climates
f. hepatica
fasciola infectin in warmer climates
f.gigantica
are a source of pasture contamination of fasciola
sheep
t.f mechanical damage to liver parenchyma is brought by adults
youngs
Caused by adults in bile ducts
chronic fasciolosis
what stage of cercaria is ingested in acute hepatic fasciolosis
metacercariae
causes black disease; what animals
clostridium novyi
sheep and cattle
Intermediate form of fasciolosis described in sheep
subacute
pressure exerted by the water inside BV
hydrostatic pressure
pressure exerted by the proteins in the blood (e.g albumin)
oncotic pressure
acute fasciolosis anemia type
normochromic
chronic fascio anemia type
hypochromic macrocytic anemia
lab of acute fascio
inc. GDH, AST/SGOT, eosinophilia, normochromic anemia
black dz spores cause fasciola in __
liver parenchyma
tx of fasciola
triclabendazole
anti-trematode drugs for adult and immature fasciola
nitroxynil, triclabendazole, diamphenetide, closantel
anti-trematode drugs for adult
clorsulon, albendazole, rafoxanide, netobimin
used to reduce snail #s
copper sulfate or sodium pentachlorophenate
what part of forage is cut to prevent metacercariae
lower
Brucellosis pathogenesis
Bacteria causes ___ ↓
Multiplies in the ___
↓
Invades ____, _, __ ___ ↓
Bacteremia for months
↓
Pregnant: ulceration of the ____ then cotyledon and villi
↓
Abortions, still birth, weak calves
Bacteria causes lymphadenitis ↓
Multiplies in the phagocytes
↓
Invades spleen, LN, mammary gland, uterus ↓
Bacteremia for months
↓
Pregnant: ulceration of the endometrium then cotyledon and villi
↓
Abortions, still birth, weak calves