SECOND GROUP OF CLASSIFICATIONS Flashcards
psychotropics -Prototype
chlorpromazine (Thorazine)
fluphenazine(Prolixin)
psychotropics action
Thought to work by blocking the release of dopamine in the brain
Some block both dopamine and serotonin receptors in the brain
psychotropics indications
psychotic disorders-schizophrenia, major depression, bipolar affective disorder
psychotropics therapeutic effects
treat extreme mania, bipolar disorder
act as tranquilizers or neuroleptics
psychotropic adverse effects
Sedation Hypotension Photophobia Photosensitivity Dry mouth Tardivedyskinesia Extrapyramidal(EPS) effects: symptoms that resemble those of Parkinson’s disease: Akathisia
psychotropic: one assessment needed for administration and f/u
assessment of all body systems before and during therapy
psychotropic desired/successful outcomes
thinking is clearer, conversation is more appropriate, fewer hallucinations
barbiturates prototype
phenobarbital
barbiturates action
Are CNS depressants that act primarily on the brainstem in an area called the reticular formation. They reduce (inhibit) the nerve impulses traveling to the area of the brain called the cerebral cortex
barbiturates indication
used as hypnotics, sedatives and anticonvulsants and anesthesia (no longer used for sleep induction)
barbiturates therapeutic effects
ultrashort acting: anesthesia for short surgical procedures, anesthesia indication, control of convulsions and reduction of intracranial pressure in neurosurgical patients
short acting: sedation and control of convulsive conditions
intermediate acting: sedation and control of convulsive conditions
long acting: epileptic seizure prophylaxis
barbiturates adverse effects
drowsiness, lethargy, dizziness, hangover (prolongation of drowsiness, lethargy and dizziness) and paradoxical restlessness or excitement.
- Vasodilation
- Hypotension
- Respiratory depression
- Drowsiness
barbiturates one assessment needed for administration and f/u
before: vital signs with attention to BP (both supine and standing measurements; pulse rate and rhythm; respiratory rate, rhythm and depth; body temperature; and presence of pain. Conduct a thorough patient assessment as well as evaluations for cautions, contraindications, and drug interactions
f/u: observe and document the patients level of consciousness or sedation; orientation to person,place and tim; respiratory rate; oxygen saturation and other vital signs
barbiturates desired/successful outcomes
an increase ability to sleep at night, fewer awakenings, shorter sleep induction time, few adverse affects such as hangover effects and an improved sense of well-being because of improved sleep
benzodiazepines prototypes
Diazepam (Valium) Lorazepam(Ativan) Alprazolam(Xanax) Oxazapam(Serax) Triazolam(Halcion) Midazolam(Versed) Chlordiazepoxide(Librium) temazepam (Restoril)
Miscellaneous nonbenzodiazepine
Zolpidem(Ambien)
benzodiazepines action
Depress the reticular-activating system of brain
Results in muting of incoming stimuli
May have muscle relaxing effect
Always a sedating and anti anxiety effect
benzodiazepines indication
sedation, anxiety management anxiety disorders Insomnia Relaxants Control of seizures Perioperativesedation Alcohol detoxification
benzodiazepines therapeutic effects
anti-anxiety agents, anticonvulsants, sedative/hypnotics
relief of anxiety
sedation
skeletal muscle relaxation
decreased seizure activity
benzodiazepines adverse effects
Suppress the Central Nervous System, so …… sedation
Other side effects: Dry mouth Disorientation Partial amnesia Respiratory depression
benzodiazepines:one assessment needed for administration and f/u
before: taking BP
f/u: assessment of alertness, orientation, and sensory/motor functioning as well as any complaints of ataxia or headaches. Eye examination. Monitoring BP and postural BP
benzodiazepines desired/successful outcomes
improved mental alertness, cognition, and mood; fewer anxiety and panic attacks; improved sleep patterns and appetite, more interest in self and others; less tension and irritability; and fewer feelings of fear, impending doom and stress
amphetamines (CNS stimulants) prototype
amphetamine salt, adderall, adderall XR
amphetamines (CNS stimulants) action
causes release of norepinephrine from nerve endings
amphetamines (CNS stimulants) indication
ADHD and narcolepsy
amphetamines (CNS stimulants) therapeutic effects
increased motor activity, mental alertness and decreased fatigue in narcoleptic patients. Increased attention span in ADHD
amphetamines (CNS stimulants) adverse effects
hyperactivity, insomnia, restlessness, tremor, sudden death, palpitations, tachycardia and anorexia
amphetamines (CNS stimulants):one assessment needed for administration and f/u
before: monitor BP, pulse and respiation ,obtain a family history of sudden death or ventricular arrhythmia, physical exam to assess for cardiac disease
f/u: monitor BP, pulse and respiration, monitor for behavior change
amphetamines (CNS stimulants) desired/successful outcomes
- improved attention span
- decreased in narcoleptic symptoms
anti epileptic drugs prototype
Phenytoin(Dilantin) one of the oldest Others: Carbamazepine(Tegretol) Valproicacid (Depakote) Lamotrigine(Lamictal) Levetiracetam(Keppra) Gabapentin(Neurontin)
anti epileptic drugs action
they alter the movement of sodium, potassium, calcium and magnesium ions. The changes in the movement of these ions result in more stabilized and less excitable cell membranes
anti epileptic drugs indication
Used to prevent and treat seizure disorders
anti epileptic drugs therapeutic effects
diminished seizure activity
anti epileptic drugs adverse effects
Drowsiness Nystagmus Dizziness Visual changes Liver inflammation Blood dyscrasias Gingival hyperplasia (Dilantin) Suicidal ideation (black box warning)
anti epileptic drugs: one assessment needed for administration and f/u
before: preform a thorough physical assessment and obtain a comprehensive health and medical history (note any type of seizure disorder, precipitating events and the duration, frequency and intensity of the seizure activity)
after: assess the pt for changes in mental status/ level of consciousness, affect, eye problems or visual disorders
anti epileptic drugs desired/successful outcomes
seizure activity is decreased or absent
antidepressants prototype
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antidepressants action
-Alter the neurotransmitters and the sensitivity
of their receptors in the CNS.
Thought that depression may be due to low
levels of neurotransmitters in the brain
So drugs may normalize abnormal
neurotransmission systems in the brain
antidepressants indication
All effective in treating depression
Post traumatic stress disorder
Eating disorders
antidepressants therapeutic effects
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antidepressants adverse effects
Drowsiness, sedation
Orthostatic hypotension
Anticholinergicside effects
antidepressants: one assessment needed for administration and f/u
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antidepressants: desired/successful outcomes
patients report feeling happier and full of energy