Sec 12 Disorders of the Oral and Genital Integument Flashcards
Most common site of Benign Alveolar Ridge Keratosis
Retromolar pad
Patterns of fissured tongue
- Central fissure alone or with smaller radiating fissures
2. Short fissures distributed evenly throughout the tongue
Presents with atrophic area on the dorsal tongue with loss of filiform papillae and slightly depressed erythematous area usually sensitive or painful
Geographic Tongue (Benign Migratory Glossitis)
Triad of fissured tongue, facial palsy, and cheilitis granulomatosa
Melkersson-Rosenthal syndrome
Most comfortable vehicle for delivering medication to the mucosa of vulva
Ointment
Manifests as bright red, shiny patches or plaques of the mucosal sites, glans and prepuce of the uncircumcised
Erythroplasia of Queyrat
May present as multiple warty red, smooth topped papules on the penile shaft
Bowenoid papulosis
Nonretractable foreskin
Phimosis
Most common disease presenting as desquamative gingivitis
Lichen planus
PFAPA Syndrome
Periodic Fever, Adenopathy, Pharyngitis, Aphthae Syndrome
Most common cause of pruritus vulvae
Candidiasis
Two histologically defined frictional keratosis
- Morsicatio Mucosae Oris
2. Benign Alveolar Ridge Keratosis
Painless, yellow brown or red, verrucous, sessile or papillary plaque on the genitalia
Verruciform xanthoma
Lilac papules or plaques with white lacy scale on the penis
Penile Lichen Planus
T or F: Vulvar psoriasis only affects keratinized skin
True
% of leukoplakia associated with carcinoma or dysplasia at time of diagnosis
20-50%
Constrictive lichenoid posthitis with a preputial band causing “hourglass” waist of the penile shaft
Genital Lichen Sclerosus
Causes of genital drug eruption
Papaverine Heparin Warfarin All-trans retinoic acid Foscarnet Nicorandil Lisinopril
Asymptomatic well-demarcated, glistening, moist, shiny, bright red, or autumn brown patches symmetrically involving the glans and inner prepuce sparing the keratinized penile shaft or foreskin
Zoon Balanitis
Rare autosominal dominant condition presenting with poorly demarcated diffuse, painless white plaques on buccal mucosa and tongue
White sponge nevus
May present with hemorrhagic crusting of lips in addition to intraoral erosions and ulcers associated with lymphoid malignancy
Paraneoplastic Pemphigus
Benign symmetric exostoses present in the midline of the hard palate or bilaterally in lingual aspect of mandible
Palatal tori
Mandibular tori
MAGIC Syndrome
Mouth And Genital ulcers with Inflamed Cartilage Syndrome
Causes tongue pigmentation with accentuation of the papillae in punctate configuration common in dark-skinned individuals
Pegylated interferon with Ribavirin
Fissured weepy lesions at the corners of the mouth often associated with Staphylococcal aureus
Angular cheilitis
Most common site for oral nevomelanocytic nevi
Palate (40%)
Sebaceous glands that present as painless papules located in bilateral symmetric on posterior buccal mucosa and vermilion of lips
Fordyce granules
Diffusely white with red punctate areas representing opening of salivary ducts from pipe smoking and reverse smoke
Nicotinic Stomatitis
Most common pathogen in denture-associated Candidiasis
Candida albicans
Hypopigmentation of the vulva with shiny or crinkled texture and purpura
Lichen sclerosus
Red scaly patches and plaques of the keratinized penis
Bowen Disease of the penis
Most common location for rhinocerebral zygomycosis
Palate
Most common site for oral pigmentation cause by Minocycline and Antimalarials with slate-gray to blue diffuse macular discoloration
Palatal mucosa
Sudden onset of oral melanotic macules should raise possibility of
Addison disease
Treatment of choice for oral melanoma
Excision with clear margins
First indication that a patient is infected with HIV
Hairy Leukoplakia
Common benign idiopathic disorder presenting as rock-hard smooth white papules or nodules on scrotum
Scrotal calcinosis
Most common sites for oral findings in Discoid lupus erythematosus
Buccal mucosa
Palate
Most worrisome complication of Lichen sclerosus
Squamous cell carcinoma of penis
White papules and plaques on either side of the linear alba on buccal mucosa, lower labial mucosa or lateral tongue caused by chewing habit
Morsicatio Mucosae Oris
T or F: Fissured tongue is a permanent condition
True
Rhomboidal area in the posterior midline of tongue, anterior to circumvallate papillae which may be slightly depressed and erythematous, or raised
Median rhomboid glossitis
Painless sloughs of desquamated tissue that lie in thin ribbons on mucosa that can be removed without pain or discomfort caused by mouthwash and caustic toothpaste
Contact Desquamation
Penile thrombophlebitis has been seen as the initial presentation of
Paraneoplastic migratory thrombophlebitis
Common condition of the tongue presenting with matted or coated appearance with history of illness and antibiotic use may have a foul or stale breath
Black hairy tongue
Flesh-colored, smooth, rounded rows of papules on the coronal margin of glans common in uncircumcised males
Pearly penile papules
Presents as asymptomatic diffuse patchy brown to black macular pigmentation of the oral mucosa and attached gingiva
Physiologic pigmentation
Annular raised double-rimmed lesions in the intergluteal cleft, on scrotum, penis and glans
Genital Porokeratosis of Mibelli
Poorly demarcated painless white papules and plaques with rough surface on keratinized mucosa of gingiva and hard palate as reaction to frictional trauma
Benign Alveolar Ridge Keratosis
Type of Lichen Planus with symmetric distribution on the buccal mucosa and tongue, usually not painful
Keratotic or Reticular form of Lichen Planus
Painless white plaque on the lateral border of tongue in immunocompromised patients (HIV/AIDS)
Hairy Leukoplakia
Most common sites for oral Squamous Cell Carcinoma
Ventral tongue
Gingiva
Floor of the mouth
Rare, low grade squamous carcinomas
Verrucous carcinoma
Warty carcinoma
Buscke-Lowenstein tumor
Giant condyloma
Most common cause of chronic vulvar dermatosis
Lichen sclerosus
Upper lip nodules
- Benign salivary gland neoplasm
- Malignant salivary gland neoplasm
- Benign nerve sheath tumor
- Benign vascular tumor
- Nasolabial cyst
Curdy yellowish-white papules or plaques which may or may not scrape off often on dorsum of tongue or palate
Thrush or Pseudomembranous candidiasis
White plaque pf questionable risk having excluded other known diseases that carry no risk for cancer
Leukoplakia
Risk factors for oral Squamous cell carcinoma
Smoking Excessive alcohol Chewing areca nut Past history of cancer/immunosuppression Family history of cancer Exposure to high risk types of HPV Age Sunlight (lip SCC)
Characterized by an acute eruption of itchy, painful, swollen plaques with central blister formation, erosion and ulceration with persistent post-inflammatory hyperpigmentation
Fixed Drug Eruption
Grayish white opalescent wrinkled area with fissures on the madibular sulcus or vestible from smokeless tobacco and carcinogens
Smokeless Tobacco Keratosis
Sore or painful annular erythematous eruption with central glassy appearance and serpiginous border surrounded by scaling in Glucagonoma syndrome
Necrolytic migratory erythema
Atrophy of the lips caused by sun damage without evidence of dysplasia
Actinic cheilitis
Tongue presenting as smooth, bald with atophic papillae associated with burning sensation and sensitivity when eating acidic, salty or crunchy foods
Atrophic glossitis
Bilateral painless fine grayish white, opalescent reticulations diffuse on the buccal mucosa or ventral tongue
Leukoedema
% of erythroplakia associated with carcinoma or dysplasia at time of diagnosis
90%
Two most common pigments of exogenous origin intraorally
Amalgam
Graphite from pencil lead
Blue to purple, smooth papules on the scrotum, penile shaft, or glans which may bleed after trauma
Angiokeratoma
Linear keratosis on the buccal mucosa bilaterally and a form of frictional keratosis
Linear alba
Most common sites for oral melanotic macule
Lower lip vermilion
Gingiva
Hard palate
Most common presentation for mucous membrane pemphigoid
Desquamative gingivitis
Poor prognosis for Penile Squamous cell carcinoma
Perineural invasion
Vascular invasion
High histological grade (sarcomatoid cancer)
White papules and plaques with minimal erythema associated with mucocutaneous disease or Hairy Leukoplakia
Hyperplastic candidiasis
Presents as an irritating, itchy, burning red scaly patch or plaque which can be found anywhere on the anogenital area
Extramammary Paget Disease
Clinical forms of oral Lichen Planus
- Keratotic/reticular
- Erythematous/erosive
- Ulcerative
Lower lip nodules
Bite fibroma
Irritation fibroma
Mucoceles
T or F: Genitalia may be the only site involved in Vitiligo
True
Most common type of oral nevomelanocytic nevi
Intramucosal nevus (66%)
Agents associated with ulcerative mucositis (ulcers on nonkeratinized sites - buccal mucosa and ventral tongue - extremely painful and several centimeters in size)
Cytarabine
Cisplatin
Painful usually bilateral maceration of the corners of the mouth with ulceration, crusting, cracking and severe cases fissuring
Angular cheilitis
Foreskin fixed in retraction
Paraphimosis
Most common dermatosis of the male anogenitalia
Psoriasis
Immune-mediated and interface stomatitis characterized by T-cell destruction of basal cells of epithelium mediated by TH1 cytokines
Oral Lichen Planus
Most effective treatment for mucous membrane pemphigoid presenting as desquamative gingivitis
Topical steroid gel
