SD Day 5 Flashcards
Avascular layer of the skin
epidermis
What are the 5 layers of the epidermis
Come Let’s Get Sun Burned
Corneum Lucidum Granulosum Spinosum Basale
This considered to be the true skin
Dermis
Two Layers of the Dermis
Papillary and Reticular
This layer of the Dermis is composed of Meissner’s Corpuscles and Free nerve endings
Papillary Layer of the Dermis
This layer of the Dermis is composed of Collagen, Elastin and reticular fibers
Reticular Layers of the Dermis
Free nerve endings in the epidermis mediate what type of sensation?
Pain and Itch
Free nerve endings in the dermis mediate what type of sensation?
Pain
Merkel’s Disks in the Stratum Spinosum mediate what type of sensation?
Touch
Meissner’s Corpuscles in the papillary dermis mediate what type of sensation?
Touch
Ruffini’s corpuscles in the papillary dermis mediate what type of sensation?
Warmth
Krause’s end bulb in the papillary dermis mediate what type of sensation?
Cold
Pacinian corpuscles in the reticular dermis mediate what type of sensation?
Pressure and vibration
This layer of the skin is mostly composed of loose connective tissue and and fat tissue
Subcutaneous Tissue
This layer of the skin functions as insulation, support, cushioning and regulation of temperature of the skin.
Subcutaneous Tissue
This is itching of the skin
Pruritus
Local redness and eruption of the skin
Rash
These are smooth slightly elevated patches on the skin
Urticaria
This is excessive dryness of the skin characterized by scaly desquamation
Xeroderma
This is the degree of elasticity of the skin.
Turgor
Normal Skin Turgor is (in seconds)?
4 seconds
abnormal = 5 seconds or more
What are the 2 factors that affect skin turgor
dehydration and aging
Pitting edema indicates?
Chronis Venous Insufficiency
Non-pitting edema indicates?
Brany edema (inflammation of the subcutaneous layer of the skin)
This is an indicator of the hepatic system, presenting with yellowing of the eye and skin.
jaundice
If bilirubin levels reach 2-3mg/dl where will jaundice present?
sclera of the eyes
If bilirubin levels reach 5-6 mg/dl where will the jaundice present?
Sclera of the eyes and the Skin
Change of lips change to cherry red this is an indication of what type of poisoning?
Carbon monoxide poisoning
Patchy Tan to Brown spots is a common skin change in what disease?
Addisons Disease
Temporary pallor occurs in what conditions?
Arterial Insufficiency, Syncope, chills and shock
This is thin depressed nails with lateral edges tilted upward forming a concave profile. AKA Spoon Nails
Koilonychia (common with iron deficiency)
Splinter nails is an indication of what type of condition?
Silent MI, Endocarditis and vasculitis
This is infection of the skin fold of skin at the margin of the nail (fungal infection from wet work)
Paronychia
Loosening of the nail plate, usually from the tip of the nail, progressing inward and from the edge of the nail moving inward.
onychylosis
What the conditions where onychylosis is often see?
Grave’s Disease, psoriasis, reactive arthritis and obsessive compulsive behaviors
Type of nails change where in lunula’s cannot be seen and have a “ground glass” appearance
Nails of Terry
Conditions where Nails of Terry are often seen
Liver Pathology, DM. Hyperthyroidism
white spots on nails, often associated with trauma, hypocalcemia, Hodgkin’s dse, renal failure, MI and malnutrition from eating disorders.
Leukonychia
These are transverse lines on nails
Beau’s Lines
Consecutive transverse lines of the nails, indicative of renal and cardiac failure, MI, Hodgkins dse, and sickle anemia.
Mee’s Lines
Proliferation of melanocytes, round, or oval shaped,
sharply defined borders, uniform color, <6mm, flat
or raised.
Common Mole (benign nervous)
Raised lesions due to proliferation of basal cells. Yellowish to brown in color with greasy, velvety and warty texture.
Seborrheic keratosis
Slow growing, raised patch with an ivory appearance, rolled border with indented center / thickened area of skin • On hair bearing sun exposed areas (face, neck, ears, hands)
Basal Cell carcinoma
Poorly defined border, flat red area, ulcer, or nodule, sun exposed areas (ear, face, lips, mouth, hand dorsum)
Central part may be ulcerated, scaly or crusted
No Metastasize*
Fairly skinned individuals > 60 y/o
Squamous cell carcinoma
- Most serious skin cancer
- Arising from Melanocytes
- Associated with intensity > duration of sunlight exposure
- Nevi that are changing or atypical, especially if >50
- Can cause pain, swelling, bleeding or sensation of itching; burning.
Malignant Melanoma
- Inflammation of the skin
- Skin is red, brown or gray; sore itchy and swollen
Dermatitis
Three Causes of Dermatitis
- Allergic/contact dermatitis: poison ivy, harsh soaps, chemicals
- Actinic: photosensitivity
- Atopic: etiology unknown, associated with allergic, hereditary, or psychological disorders
stage of dermatitis where there is red, oozing, crusting rash, extensive erosions, exudate, pruritic vesicles
Stage 1: Acute
stage of dermatitis where erythematous skin, scaling,
scattered plaques
Stage 2: Subacute
stage of dermatitis where thickened skin, increased skin marking secondary to scratching, post- inflammatory pigmentation changes
Stage 3: Chronic
- Development of areas of very dry, thin skin and sometimes shallow ulcers of the lower legs primarily as a result of venous insufficiency
- History of varicose veins or deep vein thrombosis
Stasis Dermatitis
- Chronic facial skin disorder seen most often in adults between the ages of 30 and 60 years
- Erythema, flushing, telangiectasia, papules, and pustules affecting the cheeks and nose of the face.
- Enlarged nose is often present
Rosacea
- Benign fatty fibrous yellow plaques, nodules, or tumors that develop in the subcutaneous layer of skin
- Most often associated with disorders of lipid metabolism, primary biliary cirrhosis, and uncontrolled diabetes
- May have no pathologic significance but can occur in association with malignancy such as leukemia, lymphoma, or myeloma
Xanthomas
- Superficial skin infection caused by staphylococci or streptococci
- Inflammation, small pus-filled vesicles, itching
- Contagious
- Common in children and the elderly
Impetigo
❑ Suppurative inflammation of cellular or connective tissue in or close to the skin
❑ Poorly defined and widespread
❑ By streptococcal or staphylococcal infection ❑Can be contagious
❑ Skin is red, hot and edematous
❑ Can lead to lymphangitis, gangrene, abscess and sepsis
Cellulitis
- Itching and soreness followed by vesicular eruption on the face or mouth
- Aka cold sore, recurrent herpes labialis, fever blister
Herpes 1 (Herpes Simplex)
❑ Common cause of vesicular genital eruption
❑Spread by sexual contact
❑Aka genital herpes
Herpes 2
❑Painful infection of the terminal phalanx caused by Herpes Simplex 1 and 2
❑Tingling pain or tenderness of the affected digit followed by throbbing pain, swelling and redness
Herpetic Withlow
❑Caused Varicella-zoster virus (chicken pox)
❑Pain and tingling affecting spinal or cranial nerve dermatome
❑Red papules progressing to vesicles
❑Accompanied by fever, chills, malaise, GI
disturbances
❑(+) Post herpetic neuralgic pain
Herpes Zoster (Shingles)
o Highly contagious, spread from person to person by direct contact
o Sores occur at the site of infection, mainly on the external genitals, vagina, anus, or rectum.
o Sores can also occur on the lips and in the mouth
o Transmission occurs during vaginal, anal, or oral sex
Sphyphilis
❑ Benign infection by human papilloma virus (HPV)
❑ Transmission: direct contact and autoinoculation (via broken skin)
❑ Location: hands and fingers
❑ Plantar wart: on pressure points of the feet
Warts
- Forms ring-shaped patches with vesicles or scales
- Transmission is direct contact
- Treatment: Topical or antifungal drugs
Ring worm (Tinea Corporis)
- Erythema, inflammation, pruritis, itching, pain
- Can progress to cellulitis if untreated
- Treatment: Antifungal creams
Athlete’s foot (Tinea Pedis)
Presence of fungal infection on the beard
Tinea Barbae
Presence of fungal infection on the Scalp
Tinea Capitis
Yeast type of fungal infections
candidiasis
- Bacterial infection carried by bacteria
- (+) Bulls eye appearance
Erthema Chronic Migrans (Lyme’s Disease)
❑ Chronic disease of skin with erythematous plaques covered with silvery scales
❑ Common in ears, scalp, knees, elbows, genitalia, extensor surfaces
❑ Associated with psoriatic arthritis, joint pain
❑ Topical meds may be used
❑ PT Intervention: UV light with psoralens
Psoriasis
❑ Chronic, progressive inflammatory disorder of connective tissues
❑ Characteristic red rash with raised red, scaly plaques
Lupus Erythematosus
❑ Affects only skin; flare-ups with sun exposure
❑ Causes atrophy, permanent scarring, hypo/hyperpigmentation
DISCOID LUPUS ERYTHEMATOSUS (DLE)
❑Chronic, systemic inflammatory disorder affecting multiple organ systems
❑Can be fatal
❑Symptoms: Fever, butterfly rash across bridge of nose, arthritis, photosensitivity, Raynaud’s Phenomenon
Systemic Lupus Erythematosus
Chronic, autoimmune diffuse disease of connective tissues causing fibrosis of skin, joints, blood vessels, GI tract, lungs, heart, kidneys
Scleroderma
❑ Affecting the connective tissues
❑ Inflammation of the muscle and skin
❑ Skin rash and proximal mm weakness
❑ (+) Gottron’s sign
❑ (+) Heliotrope rash
❑ (+) Shawl sign
❑ (+)Mechanic’s Hands
Dermatomyositis