SCT II - Carbohydrate Metabolism II (Glycogenolysis/Glycogenesis Regulation)

Question 1

What activates glycogenolysis (inhibits glycogenesis)?

Answer 1

1. Glucagon & Epinephrine
2. High AMP (activate glycogen phosphorylase)
3. cAMP (activates glycogen phosphorylase) via Glucagon & Epinephrine
4. Ca2+ (activates glycogen phosphorylase)

Question 2

What activates glycogenesis (inhibits glycogenolysis)?

Answer 2

1. Insulin
2. High ATP (inhibit glycogen phosphorylase)
3. Glucose

Question 3

How does cAMP promote glycogenolysis?

Answer 3

high cAMP activates protein kinase A

high cAMP is induced by glucagon & epinephrine

Question 4

How does G-6-P play a role in glycogenesis?

Answer 4

G-6-P converts glycogen synthase from inactive form to active form - However, it cannot impact the active form