SCT I - Glycolysis Flashcards
STEP 1
Glucose → G-6-P
Glucose → Glucose-6-Phosphate | Hexokinase
- ATP → ADP
STEP 2
G-6-P → F-6-P
Glucose-6-Phosphate → Fructose-6-Phopshate | Glucose-6-Phopshate Isomerase (GPI)
STEP 3
F-6-P → F-1,6-BP
Fructose-6-Phosphate → Fructose-1,6-Bisphopshate | Phosphofructo Kinase 1 (PFK1)
- ATP → ADP
STEP 4
F-1,6-BP → GA-3-P
Fructose-1,6-Bisphosphate → Glyceraldehyde-3-Phosphate | Aldolase
OTHER STEP 4
F-1,6-BP → DHAP
DHAP → GA-3-P
Fructose-1,6-Bisphosphate → Dihydroxyacetone Phosphate | Aldolase
Dihydroxyacetone Phosphate → Glyceraldehyde-3-Phosphate | Triosephosphate Isomerase 1 (TPI1)
- Important for lipid metabolism
STEP 5
GA-3-P → 1,3-BPG
Glyceraldehyde-3-Phosphate → 1,3-Bisphosphoglycerate | Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
- NAD+ → 2x NADH
STEP 6
1,3-BPG → 3-PG
1,3-Bisphosphoglycerate → 3-Phosphoglycerate | Phosphoglycerate Kinase
- ADP → 2x ATP
STEP 7
3-PG → 2-PG
3-Phosphoglycerate → 2-Phosphoglycerate | Phosphoglycerate Mutase
STEP 8
2-PG → PEP
2-Phosphoglycerate → Phospho-Enol-Pyruvate | Enolase
- H2O OUT
STEP 9
PEP → Pyruvate
Phospho-Enol-Pyruvate → Pyruvate | Pyruvate Kinase
- ADP → 2x ATP