Screening Flashcards

1
Q

What is the primary objective of screening?

A

Detection of a disease in its early stages in order to treat it and deter its progression

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2
Q

What is the secondary objective of screening?

A

Reduce cost of disease management by avoiding costly interventions required at later stages

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3
Q

What are the 3 types of screening?

A
  1. Mass
  2. Selective
  3. Periodic
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4
Q

What is mass screening?

A
  • Applied to an entire population

- Ex. cholesterol screening at a health fair

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5
Q

What is selective screening?

A
  • Targeted
  • Performed for specific high-risk populations
  • Ex. TB tests for hospital employees
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6
Q

What is periodic screening?

A
  • Screen a discrete, but well, subgroup of the population on a regular basis over time for predictable risks or problems
  • Ex. cervical cancer
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7
Q

What are advantages of screening?

A
  • Simplicity (for some)
  • Target individuals or groups
  • Options of one-test or multiple-test
  • Opportunity for health education
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8
Q

What are disadvantages of screening?

A
  • Not 100% accurate

- Will have false positives and false negatives

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9
Q

What are implications of false positive?

A
  • Undo worry
  • Stigma
  • More invasive testing
  • Unnecessary treatment
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10
Q

What are implications of false negative?

A
  • May lose opportunity for early intervention

- May engage in risky behavior due to negative status

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11
Q

How do we select a screenable disease?

A
  • Significance: is this a true concern? Level of threat?
  • Detection: Can we screen for it? Do we have the technology?
  • Should screening be done: What does evidence say and what is the benefit of knowing?
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12
Q

What is sensitivity?

A
  • The ability of a test to correctly identify people who have the condition being tested for
  • Identify true positives
  • Poor sensitivity = increased false negatives
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13
Q

What is specificity?

A
  • The ability of a test to correctly identify people who do not have the condition being tested for
  • Identify true negatives
  • Poor specificity = increased false positives
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14
Q

What is the equation for sensitivity?

A

TP/(TP+FN)

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15
Q

What is the equation for specificity?

A

TN/(TN+FP)

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16
Q

Who are the people with the disease who test +?

A

True positive

17
Q

Who are the people with the disease who test -?

A

False negative

18
Q

Who are the people without the disease who test +?

A

False positive

19
Q

Who are the people without the disease who test -?

A

True negative