Scientist Names

Question 1

Christiane Nüsslein-Volhard

Answer 1

Identify all genes in zebrafish development. Early 1990’s.

Question 2

Edward Lewis

Answer 2

First systematic attempt to identify all genes involved in Drosophila development

Question 3

Christiane Nüsslein-Volhard and Eric Wieschaus

Answer 3

Developed Lewis’s studies for full understanding of genetic control in Drosophila, genetic control of early embryonic develpment

Question 4

Sydney Brenner, Sir John Sulston and Robert Horvitz

Answer 4

Used nematode for genetic regulation of organ development and programmed cell death

Question 5

Aristotle

Answer 5

First person to describe embryonic development

Question 6

William Harvey

Answer 6

Epigenesis - physician to King James I and King Charles I

Question 7

Antonie van Leeuwenhoek

Answer 7

Discovered spermatazoa in 1677

Question 8

Nicolaas Hartsoeker

Answer 8

Sperm artist

Question 9

Nicolas Malebranche

Answer 9

Suggested sperm contained all genetic info of future generations

Question 10

Marcello Malpighi

Answer 10

First person to observe chick development under microscope -> chicks preformed in fertilised egg

Question 11

Hans Driesch

Answer 11

Sea urchin embryos are capable of replacing parts that had been deleted -> embryonic regulation

Question 12

August Weismann

Answer 12

Zygote nucleus contained a number of special factors called determinants

Question 13

Wilhelm Roux

Answer 13

Frog egg was a mosaic of different cell determinants

Question 14

Edwin Conklin

Answer 14

Development of the differently coloured cytoplasm in larvae

Question 15

Laurent Chabry

Answer 15

Each blastomere was responsible for producing a particular set of larval tissues (even in isolation)

Question 16

Hiroki Nishida and Kaichiro Sawada

Answer 16

RNA hybridisatioin to identify maternal mRNAs that are localised to the vegetal hemisphere of ascidian eggs

Question 17

Hans Spemann

Answer 17

Regulative development in 2 cell newt embryo

Question 18

Pieter Nieuwkoop

Answer 18

Mesoderm induction occurs during blastula stages induced in animal fragment by vegetal fragment in axoloti and xenopus laevis embryos

Question 19

Ernst Hadorn

Answer 19

Imaginal discs in drosophila differentiate as expected

Question 20

Hans Spemann

Answer 20

First SCNT theory

Question 21

Robert Briggs and Thomas King

Answer 21

First successful cloning of an animal by SCNT, Leopard frog (Rana pipiens)

Question 22

Steen Willadsen

Answer 22

First successful attempt to clone a mammal by SCNT- sheep embryo

Question 23

Keith Campbell and Ian Wilmut

Answer 23

Dolly

Question 24

Harold Weintraub

Answer 24

Transdifferentiation

Question 25

Kazutoshi Takahashi and Shinya Yamanaka

Answer 25

Oct4, Sox2, Myc and Klf4 sufficient to induce pluripotency