Gastrulation Flashcards
Invagination
Folding of the surface epithelium of the blastula usually at the vegetal pole to form a central tube, archenteron
Blastopore
Point of invagination
Involution
Similar to invagination and also forms an archenteron that extends towards the animal pole from a blastopore
Ingression
Migration of individual cells from surface epithelium into the interior of the embryo
Primary mesenchyme cells
Apical surface of vegetal plate form bottle cells which ingress into blastocoel, remaining clustered at vegetal plate to form precursors of the mesoderm
Cadherins
Ca2+ dependent adhesion molecules
Convergent-extension
Cells become elongated perpendicular to axis of elongation and form actin and myosin rich lamellipodia at opposite poles. Lamellipodia used to exert traction on each other and drive cell intercalation narrowing invaginating tube and elongating towards animal pole
Secondary mesenchyme cells
Complete elongation of archenteron. Form at invaginating tip of archenteron and produce filopodia
Filopodia
Long cytoplasmic extensions that search for basal surface of animal pole§
Trophoblast
Outer epithelium at 16-32 cell stage of holoblastic cleavage, forms chronic layers of placenta
Inner cell mass
Small population of internal mesenchyme- like cells at 16 to 32 cell stage
First step in development of mammalian ICM
Formation of hypoblast and epiblast
Hybolast layer is adjacent to
Blastocoel
Heuser’s membrane
Layer of exraembryonic endoderm deriving from hypoblast spreading around trophoblast lining the blastocoel
Yolk sac
Enclosed cavity by Heuser’s membrane
Meckel’s diverticulum
Small bulge in the small intenstine and is most frequent congenital malformation of digestive tract
Amniotic membrane
Layer of flattened epithelial, extraembroynic ectoderm,cells lining amnion formed by epiblast