schizophrenia - biological causes Flashcards
3 suggested biological causes
neurotransmitters, genes, brain structure
genes - prevalence
prevalence remains constant despite growing world population
genes - twin study - example
Gottesman and Shields (1966)
studied concordance rate for schizophrenia in 57 twin pairs
54% of MZ twins both had sz
18% of DZ twins both had sz
would be expected to be 100% in MZ twins because they share the same genes
genes - family studies
higher prevalence in siblings and other relatives of sz sufferers.
brain structure cards in seperate deck
in seperate deck
neurotransmitters - dopamine hypothesis
excess of dopamine activity in the brain of sz patients
links to D2 receptor malfunction - means that dopamine works for longer and in excess
neurotransmitters - glutamate
regulates dopamine and the function of it
the glutamate problem may be causing the problem with dopamine, resulting in sz
neurotransmitters - serotonin
excess of serotonin activity - causes negative sz symptoms