Schizophrenia Flashcards

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1
Q

% of homeless people with schiz.

A

10-20%

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2
Q

Age of onset

A

16-25

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3
Q

Suicide rates

A

8-10%

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4
Q

Amount of canadian

A

300,000– 1/12 of hospital beds

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5
Q

Costs

A

6.85 billion

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6
Q

% of patients with auditroy hallucinations

A

70%

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7
Q

Postive Symptoms

A

Exaggerated, distorted adaptations of normal behaviour– delusions, hallucinations, disorganized thought and speech

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8
Q

Negative Symptoms

A

Absence of typical behaviours and experiences

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9
Q

Avolition

A

Apathy and loss of motivation

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10
Q

Anhedonia

A

Inability to feel pressure and lack of emotional response

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11
Q

Hallucinations

A

Misinterpretations of sensory perceptions that occur while a person is awake and conscious, and in the absence of corresponding stimuli

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12
Q

Delusions

A

Implausible beliefs that persist despite contradictory evidence

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13
Q

Persecutory Delusions

A

Believe they are being pursued or targeted– most common

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14
Q

Referential delusions

A

Belief that common, meaningless occurances have significant and personal relevance

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15
Q

Somatic delusions

A

Related to patient’s body– organs have turned to dust

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16
Q

Religious delusions

A

Belief that biblical passages offer the way to destroy or save the world

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17
Q

Delusions of grandeur

A

Belief in divine or special powers that can control the course of history

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18
Q

Loose Associations

A

Shifts quickly from one topic to another

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19
Q

Word salad

A

Many different, unrelated topics

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20
Q

Neologisms

A

Newly created word whose meaning is unknown to others

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21
Q

Perseveration

A

Repetition of the same verbal or motor response

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22
Q

Thought blocking

A

Sudden silences in persons speech

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23
Q

Abnormal motor behaviour

A

Deficits in motor functioning and difficulty with goal directed behaviour

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24
Q

Catatonic behaviour

A

Reduction n responsiveness to environment

25
Q

Wavy flexibility

A

Allowing others to move their body into new positions and maintaining it

26
Q

Affective flattening

A

Lack of emotional responsiveness and failing to convey feeling

27
Q

Alogia

A

Poverty of speech

28
Q

6 DSM criteria

A

Characteristic symptoms
Social or occupational dysfunction
Persistence for at least 6 months
Exclusion of schizoaffective or mood disorders
Exclusion of substance abuse or medical conditions
Consideration of autism or communication disorder

29
Q

3 phases of schiz

A

Prodromal
Active
Residual

30
Q

Prodromal

A

Clear deterioration of functioning

31
Q

Active

A

2 or more symptoms, one must be positive, lasts at least 1 month

32
Q

Residual

A

Attenuated symptoms following active phase

33
Q

Schizophreniform disorder

A

Lats 1-6 months

34
Q

Brief psychotic disorder

A

Less than 1 month

35
Q

Endophenotypes

A

Hereditary marker that is closely associated but is not a direct symptom of disorder– vulnerability

36
Q

Cognitive subtypes

A

Subgroups on basis of impaired problem solving and memory deficits

37
Q

Kraepelin

A

Noted it ran in families, frontal and temporal lobes involved

38
Q

Schizophrenogenic

A

Cold and rejecting behaviour causes schizophrenia

39
Q

Collective unconcious

A

Jung– Symbols and myths are shared unconsciously in a culture

40
Q

Hypokrisia

A

Nerve cells are abnormally reactive to incoming stimulation

41
Q

Aversive drift

A

Brain amplifies feelings of pain and weakens pleasure– makes social contact unpleasant

42
Q

Schizotype

A

Person experiencing cognitive slippage and aversive drift

43
Q

One episode only, complete recovery

A

20%

44
Q

Several episodes, return to normal functioning

A

35%

45
Q

Several episodes, never return to normal

A

10%

46
Q

Continual deterioration, poor er functioning between episodes

A

35%

47
Q

Reducton in lifespan

A

10 years

48
Q

Prevalence

A

1% men= women

49
Q

Schizoaffective disordr

A

Grandiose, jealous, persecutory

50
Q

MZ concordance rate

A

48%

51
Q

Penetrance

A

Proportion of peoplewith a genetic change that exhibit signs of a disorder

52
Q

Cumulative liability

A

Combined risk for developing an illness that accumulates over multiple factors and over time

53
Q

Left temporal lobe

A

Attention, speech, language, visual understanding

54
Q

3 systems in dopamine hypothesis

A

Nigrostriatal
Mesocortical
Mesolimbic

55
Q

D2 receptors

A

Postive symptoms, benefit from antipsychotics

56
Q

D1

A

Negative symptoms

57
Q

Basal ganglia

A

Abnormal motor behaviour

58
Q

Right temporal lobe

A

Flat affect, aprosodia