Schizophrenia

Question 1

Which NTs are involved

Answer 1

DA, NE, 5-HT, GLU, GABA

Question 2

Which NT is connected to most of the symptoms of schizophrenia

Answer 2

DA

Question 3

What are the four major pathways of the brain involved with schizophrenia

Answer 3

Mesolimbic
Mesocortical
Nigrostriatal
Tuberinfundibular

Question 4

Mesolimbic & schizophrenia

Answer 4

originates in the ventral tegmentum and projects to areas of the imibic system

Associated functions are:

memory
emotion
arousal
pleasure

Excess activity implicated with positive signs of the illness

Question 5

Mesocortical & schizophrenia

Answer 5

Originates in the ventral tegmentus and projects into the cortex

Associated functions are:

cognition
planning
problem solving
motivation
reinforcement in learning

Diminished activity implicated with negative symtpoms of schizophrena:

Question 6

Nigrostriatal - schizophrenia

Answer 6

originates in the substantia nigra and terminates in the striatum of the basal ganglia

Associated functions are:

motor control

Degeneration is associated with Parkinsons Disease and involuntary psychomotor symptoms of schizophrenia

Question 7

Tuberinfundibular & schizophrenia

Answer 7

originates in the hypothalamus and projets to the pituitary gland

Associated functions are:

endocrine
digestion
metabolism
hunger
thirst
temperature control
sexual arousal

Implicated in certain endocrine abnormalities associated with schizophrenia