Depression

Question 1

NTs involve with depression

Answer 1

5-HT, NE

Question 2

Cell bodies with depression - 5-HT

Answer 2

raphe nuclie in the brainstem and project throughout the forebrain, prefrontal cortex, cerebellum, and limbic system

Question 3

Cell bodies with depression - NE

Answer 3

oringinate in the locus ceruleus and project throughout the forebrain, prefrontal cortex, cerebellum, and limbic system

Question 4

Areas of the brain affected with depression

Answer 4

Hippocampus - memory impairment, feelings of worthlessness, hopelessness, and guilt

amygdala: anhedonia, anxiety, reduced motivations
hypothalamus: increased or decreased sleep and appetitie, decreased energy and libido

prefrontal cortex: depressed mood, problems with concentration

cerebellum: psychomotor retardation//agitation
Other limbic structures:
emotional alteration

Question 5

NE reuptake inhibition results in

Answer 5

remors, cardiac arrhythmias, sexual dysfunction, and HTN

Question 6

5-HT reuptake inhibition results in

Answer 6

GI disturbances, increased agitation, sexual dysfunction

Question 7

DA reuptake inhibition reults in

Answer 7

psychomotor activation (EPS)

Question 8

ACh blockage resutls in

Answer 8

dry mouth, blurred vision, constipation, and urinary retention