schizophrenia Flashcards
what age is it most common in and mc in M or F?
25y/o
F=M
what is schizophrenia?
disassociation from reality for 28+ days NOT due to substance misuse
what is it called if you get these symptoms for less than 28 days?
transient psychosis
which lobe is affected in schizophrenia?
temporal
what are the 2 hypothesis names?
neurodevelopment hypothesis
Neurotransmitter hypothesis
what is the neurodevelopmental hypothesis?
hypoxic ischemic injury (other birth comps = poorer brain development and increased risk)
what is the neurotransmitter hypothesis?
high mesolimbic therefore +ve symptoms and low mesocortical therefore -ve Sx
RF for schiz?
Family Hx 1^ relative
smoking cannbis in youth
traumatic birth
MHI
Trauma + abuse
what are some types of schizophrenia?
paranoic schizophrenia (persecutory) - MC
Hebephrenic (young Px)
simple
catatonic
Undifferentiated
what are the 2 types of Sx you can get?
how many of each do you need for a diagnosis?
Schnider 1^ rank
(1 of these)
2^ rank
(2 of these)
what are the Schneider 1^ rank Sx?
-delusional perception
-Thought alienation: Insertion, withdrawal, broadcast, word salad
-3rd person auditory hallucination
-Passivity
what are the 2^ rank Sx?
-Non auditory hallucinations (eg, visual, tactile)
- Catatonia (abrupt posturing)
-delusions
-low insight
what happens in term of the DVLA in schizophrenia patients?
Notify DVLA
Can’t drive until 3+ months well on Tx with psychiatry report
Psychosis Ddx?
Drug induced
schizophrenia
depression
post partum
huntingtons
syphillis
schizoaffective
Drugs causing psychosis?
steroids
benzos
cocaine
meth
LSD
ecstasy
