Other meds

Question 1

What is lithium used as?

Answer 1

Mood stabiliser
in bipolar affective disorder

Question 2

what type of drug is it?
does it have a wide or narrow therapeutic index?
what is the index?

Answer 2

CAMP-i (cyclic AMP inhibitor)
Narrow (0.4-1.0 mmol/L)

Question 3

what 3 drugs does lithium interact with and to cause what?

Answer 3

NSAIDS (to cause AKI)
Diuretics (to increase dehydration)
ACE - i

Question 4

What does lithium con stand for?

Answer 4

Leukocytes
Insipidus (diabetes)
Tremor (fine = normal, coarse = toxicity)
Hydration low and HypOthyroid
Increased thirst
Urine output high
Mums beware (teratogenic)
CV issues eg, Ebstein and arrhythmias)
Oedema
Nephrotoxic (stop lithium)

Question 5

what level of lithium classes as lithium toxicity and what is the acronym to remember symptoms?

Answer 5

1.5+ mmol/L
LITHIUM CON

Question 6

When and what to measure when prescribing lithium?

Answer 6

Serum Li 12 hr post dose, Weekly till stable then 3 monthly

Question 7

what is ebstein anomaly?

Answer 7

heart defect in baby
don’t give lithium to pregnancy women

Question 8

what tests do we do (general)? for Li

Answer 8

FBC, U+E, TFT, eGFR, BMI, ECG

Question 9

What can happen months after stopping Li?
what is the acronym?

Answer 9

Neurological Sx
SILENT

Question 10

What does SILENT stand for?
what Sx?

Answer 10

Syndrome of Irreversible Lithium Effectuated Neurotoxicity
Cerebellar Sx
EPSE
Dementia

Question 11

What are some other mood stabilisers?

Answer 11

Carbamazepine
Sodium valproate
(also work as anti epileptics)

Question 12

Benzodiazepines
what type of medications are they?
used in?

Answer 12

GABA agonists
sedating Px
alcohol withdrawal
status epilepticus

Question 13

examples of benzos?

Answer 13

Chlordiazepoxide (medium)
Diazepam (short)
Lorazepam (long)

Question 14

SE of benzos?
overdose Tx?

Answer 14

Resp depression
sedation
amnesia

IV Flumenazil

Question 15

Anxiolytic (hypnotic)
eg?
type of drug?
helps with?

Answer 15

Zopiclone
GABA agonist
helps insomnia

Question 16

what does ECT stand for?

Answer 16

electrocompulsive therapy

Question 17

what is ECT?
used in which patient?

Answer 17

Electrode guided current to brain parenchyma in High suicidality, refractory depression, severe mania, catatonic schizophrenia

Question 18

Complication and CI of ECT?

Answer 18

amnesia
Confusion

Child <12y, htn, MI <3months ago

Question 19

what are 4 types of talking therapy?

Answer 19

CBT
DBT
IPT
Couple therapy

Question 20

what does CBT stand for?
what is it used for?
how is it used?

Answer 20

cognitive behavioural therapy
change NEGATIVE thoughts
breaks problems into STEAP (situation, thoughts, emotions, actions, physical feelings)

Question 21

what does DBT stand for?
what is it used for?

Answer 21

Dialectical behaviour therapy
chnaged negative thoughts like CBT and promotes ACCEPTANCE

Question 22

what does IPT stand for?
what is it used for?

Answer 22

interpersonal therapy
resolving relationship problems

Question 23

what is couples therapy used to do?

Answer 23

promote communication and strength
Reduce emotional avoidance
Modify dysfunctional behaviour