Other meds Flashcards

1
Q

What is lithium used as?

A

Mood stabiliser
in bipolar affective disorder

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2
Q

what type of drug is it?
does it have a wide or narrow therapeutic index?
what is the index?

A

CAMP-i (cyclic AMP inhibitor)
Narrow (0.4-1.0 mmol/L)

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3
Q

what 3 drugs does lithium interact with and to cause what?

A

NSAIDS (to cause AKI)
Diuretics (to increase dehydration)
ACE - i

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4
Q

What does lithium con stand for?

A

Leukocytes
Insipidus (diabetes)
Tremor (fine = normal, coarse = toxicity)
Hydration low and HypOthyroid
Increased thirst
Urine output high
Mums beware (teratogenic)
CV issues eg, Ebstein and arrhythmias)
Oedema
Nephrotoxic (stop lithium)

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5
Q

what level of lithium classes as lithium toxicity and what is the acronym to remember symptoms?

A

1.5+ mmol/L
LITHIUM CON

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6
Q

When and what to measure when prescribing lithium?

A

Serum Li 12 hr post dose, Weekly till stable then 3 monthly

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7
Q

what is ebstein anomaly?

A

heart defect in baby
don’t give lithium to pregnancy women

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8
Q

what tests do we do (general)? for Li

A

FBC, U+E, TFT, eGFR, BMI, ECG

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9
Q

What can happen months after stopping Li?
what is the acronym?

A

Neurological Sx
SILENT

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10
Q

What does SILENT stand for?
what Sx?

A

Syndrome of Irreversible Lithium Effectuated Neurotoxicity
Cerebellar Sx
EPSE
Dementia

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11
Q

What are some other mood stabilisers?

A

Carbamazepine
Sodium valproate
(also work as anti epileptics)

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12
Q

Benzodiazepines
what type of medications are they?
used in?

A

GABA agonists
sedating Px
alcohol withdrawal
status epilepticus

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13
Q

examples of benzos?

A

Chlordiazepoxide (medium)
Diazepam (short)
Lorazepam (long)

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14
Q

SE of benzos?
overdose Tx?

A

Resp depression
sedation
amnesia

IV Flumenazil

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15
Q

Anxiolytic (hypnotic)
eg?
type of drug?
helps with?

A

Zopiclone
GABA agonist
helps insomnia

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16
Q

what does ECT stand for?

A

electrocompulsive therapy

17
Q

what is ECT?
used in which patient?

A

Electrode guided current to brain parenchyma in High suicidality, refractory depression, severe mania, catatonic schizophrenia

18
Q

Complication and CI of ECT?

A

amnesia
Confusion

Child <12y, htn, MI <3months ago

19
Q

what are 4 types of talking therapy?

A

CBT
DBT
IPT
Couple therapy

20
Q

what does CBT stand for?
what is it used for?
how is it used?

A

cognitive behavioural therapy
change NEGATIVE thoughts
breaks problems into STEAP (situation, thoughts, emotions, actions, physical feelings)

21
Q

what does DBT stand for?
what is it used for?

A

Dialectical behaviour therapy
chnaged negative thoughts like CBT and promotes ACCEPTANCE

22
Q

what does IPT stand for?
what is it used for?

A

interpersonal therapy
resolving relationship problems

23
Q

what is couples therapy used to do?

A

promote communication and strength
Reduce emotional avoidance
Modify dysfunctional behaviour