Addictive behaviours Flashcards
what pathway does addiction act on?
mesolimbic pathway
How many dependence terms do you need to mean your dependent?
3+ means dependent (in 12 month period)
What are the terms of dependence?
withdrawal Sx - uses substance to avoid withdrawal Sx onset
Tolerance
Narrow repertoire (one type of drug/alcohol)
Craving
Loss of control
Rapid reinforcement - quick return to old level after stopping
Primacy - taken precedence over psychological need
Continued use despite harm
Substance abuse –>
Misuse –>
excessive use
2^ use
Alcohol:
what does it work on in the body?
what happens overall?
what Sx?
GABA ergic (inhibitory) CNS retardation - slows you down
high adipose mass
high cortisol
low co ordination (cerebellar Sx)
low Resp rate
Sx of alcohol intoxication?
high sexual arousal
ataxia
slurred speech
high confidence
irritable
change in GCS
Vomiting
Sx of alcohol withdrawal and time frames?
6-12hr
12-24hr
36hr
72hr
6-12hr: anxiety + fine tremor
12-24: hallucinations
36hr: seizure (gen tonic clonic)
72hr: delirium tremens (coarse tremor, altered mental state, change in GCS)
What would you see on the bloods in someone who drinks alcohol?
Non megaloblastic macrocytic anemia
High GGT
High ALP
High CDT
which 2 questionnaires are done in alcohol addiction?
why are they done?
CAGE - Screening
AUDIT - Dx
what are the CAGE questions?
what score is needed?
2+/4
should you Cut down?
Annoyed at others telling you to cut down?
Guilty?
Eye opener? (drink in the morning as an eye opener)
what score is needed from AUDIT?
8+/10
once stable, what diagnosis questionnaire is used for alcohol addiction?
CLWA - Ar
Clinical Withdrawal Assess - alcohol related
what blood alcohol concentration (BAC) makes it illegal to drive?
0.08%+
what % of alcoholics develop liver cirrhosis?
20%
What is acute Tx for alcohol withdrawal?
What do you give if a Px has liver sclerosis?
IV Chlordiazepoxide (med acting benzo) - Tx of withdrawal
IV lorazepam