Depression, Self harm + suicide, Bipolar Flashcards
what is the ratio of F:M with depression?
who is more suicidal?
F>M (2:1)
Males
what is the definition of depression?
2+ weeks of anhedonia (loss of interest in things prev interested in), low mood and low energy most days
what are some bio-psycho-social risk factors for depression?
Bio: chronic pain, post partum, steroid use, Low T4
Psycho: Trauma, low esteem, abuse
Social: Bereavement, divorce, very stressed
what are the 2 hypothesis of depression?
explain them?
stress - vulnerability = diff ppl = diff thresholds
Monoamine hypothesis = low DA, serotonin, NAd
Sx of depression Acronym?
SIGE CAPS
SIGE CAPS?
Suicidality/self harm
Interest Low
Guilt + worthlessness
Energy low
Concentration Low
Appetite low
Psychomotor retardation
Sleep low
what are the Sx in atypical depression?
Tx?
high appetite, sleep + mood may be okay on good occasions, catatonia, VERY SENSITIVE
Tx: CBT + MAOI/SSRI
what bloods would we do for depression?
FBC, U+E, TFT, Prolactin, syphillis serology, B12 + Folate
what 4 questionnaires are done?
PHQ9
HADS
BDI - II
Edinburgh
PHQ9 (scores and levels?)
HADS
BDI-II
Edinburgh
Used in?
PHQ9 - used in community
0-4 = none, 5-9 = mild, 10-14 = mod, 15+ = severe
HADS (only hospital use) - anxiety and depression
BDI-II (Beck depression inventory - self reporting)
Edinburgh (post natal depression)
What is the criteria for:
subclinical
Mild
moderate
severe
subclinical = 4 or less SIGECAPS
Mild = 5 or more SIGECAPS + little functional impairment
Moderate = 5 or more SIGECAPS + marked functional impairment
severe = 5 or more SIGECAPS + marked functional impairment +/- psychosis
Tx for mild depression?
- CBT (group/individual) + advice 12-16 weeks
- SSRI (can give first if want Tx)
Mod/severe depression Tx?
Refractory/severe Tx?
SSRI + high intensity CBT
Can consider ECT
IAPT referral for what?
what does IAPT stand for?
Improving access to psychological therapies
NHS initiative for mild-moderate depression
Non pharmacological Tx for depression?
CBT
IPT (interpersonal)
Psychodynamic therapy
seasonal affective disorder
describe its nature and time its worse?
Tx?
Recurrent
winter
Tx= light therapy, SSRI
what is dysthymia?
Tx?
Subclinical depression for 2+ years
Tx = low intensity CBT