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PHM 701 > Schizophrenia > Flashcards

Schizophrenia Flashcards

1
Q

More EPS FGA or SGA?

A

FGA

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2
Q

Chlorpromazine FGA or SGA?

A

FGA

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3
Q

Fluphenazine FGA or SGA?

A

FGA

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4
Q

Haloperidol FGA or SGA?

A

FGA

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5
Q

Perphenazine FGA or SGA?

A

FGA

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6
Q

Thioridazine FGA or SGA?

A

FGA

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7
Q

Thiothixenne FGA or SGA?

A

FGA

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8
Q

Aripiprazole FGA or SGA?

A

SGA

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9
Q

Asenapine FGA or SGA?

A

SGA

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10
Q

Brexpiprazole FGA or SGA?

A

SGA

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11
Q

Cariprazine FGA or SGA?

A

SGA

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12
Q

Clozapine FGA or SGA?

A

SGA

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13
Q

Iloperidone FGA or SGA?

A

SGA

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14
Q

Lumateperone FGA or SGA?

A

SGA

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15
Q

Lurasidone FGA or SGA?

A

SGA

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16
Q

Olanzapine FGA or SGA?

A

SGA

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17
Q

Paliperidonee FGA or SGA?

A

SGA

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18
Q

Pimavanserin FGA or SGA?

A

SGA

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19
Q

Quetiapine FGA or SGA?

A

SGA

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20
Q

Risperidone FGA or SGA?

A

SGA

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21
Q

Ziprasidone FGA or SGA?

A

SGA

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22
Q

High potency FGA have

A

High EPS
Low Anticholinergic

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23
Q

Low potency FGA have

A

Low EPS
High Anticholinergic

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24
Q

High potency FGA are

A

Fluphenazine
Haloperidol

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25
Q

Low potency FGA are

A

Thioridazine
Chlorpromazine

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26
Q

Acute injectable FGA

A

Chlorpromazine
Haloperidol
Fluphenazine

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27
Q

Long acting injectable FGA

A

Fluphenazine
Haloperidol

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28
Q

Acute injectable SGA

A

Olanzapine
Ziprasidone

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29
Q

Long acting injectable SGA

A

Aripiprazole
Olanzapine
Risperidone
Paliperidone

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30
Q

Aripiprazole main clinical pearl

A

Impulsivity

31
Q

Asenapine main clinical pearl

A

New topical patch available

32
Q

Brexpiprazole main clinical pearl

A

Impulsivity

33
Q

Clozapine main clinical pearl

A

Blood dyscrasia
Metabolic
Constipation
QT prolongation
Seizure

34
Q

Iloperidone main clinical pearl

A

Orthostatic hypotension
Slow titration

35
Q

Lurasidone main clinical pearl

A

do not use with strong CYP3A4 inhibitor and inducer

36
Q

Lumateperone main clinical pearl

A

Don’t take in 3rd trimester

37
Q

Olanzapine main clinical pearl

A

Metabolic risks
DRESS

38
Q

Paliperidone main clinical pearl

A

EPS
Prolactin

39
Q

Pimavanserin main clinical pearl

A

No dopamine

40
Q

Quetiapine main clinical pearl

A

Sedation
Anticholinergic effects
Cataracts

41
Q

Risperidone main clinical pearl

A

EPS
Prolactin

42
Q

Ziprasidone main clinical pearl

A

QT prolongation

43
Q

SGA with Black box warning for suicidal thoughts

A

Aripiprazole
Lurasidone
Olanzapine
Paliperidone
Quetiapine
Risperidone

44
Q

APS Sedation AEs

A

Chlorpromazine
Clozapine
Quetiapine
Thioridazine

45
Q

APS EPS AEs

A

Chlorpromazine
Fluphenazine
Haloperidol
Perphenazine
Thioridazine
Thiothixene

46
Q

APS Anticholinergic AEs

A

Chlorpromazine
Clozapine
Thioridazine

47
Q

APS Orthostasis AEs

A

Chlorpromazine
Clozapine
Iloperidone
Thioridazine

48
Q

APS Weight gain AEs

A

Clozapine
Olanzapine

49
Q

APS Prolactin AEs

A

Chlorpromazine
Fluphenazine
Haloperidol
Paliperidone
Perphenazine
Risperidone
Thioridazine
Thiothixene

50
Q

APS Cardiovascular AEs

A

Haloperidol
Chlorpromazine
Clozapine
Iloperidone
Ziprasidone

51
Q

Painful prolonged muscle contractions, involuntary facial movements, arms

A

Acute dystonias

52
Q

Bradykinesia, tremor, pill rolling

A

Pseudo-parkinsonism

53
Q

Restlessness, pacingm shuffling

A

Akathisia

54
Q

Tongue thrusting, chewing, lip smacking

A

Tardive dyskinesia

55
Q

Acute dystonia treatment

A

Anti cholinergics
IM benzos
Decrease dose or d/c

56
Q

Pseudo-parkinsonism treatment

A

Anti cholinergic
Decrease dose or d/c

57
Q

Akathisia treatment

A

Beta blockers
Decrease dose or d/c

58
Q

Tardive dyskinesia treatment

A

Prevention
D/c
Do not use anticholinergics because they will mask sxs

59
Q

Quitting smoking can ____ clozapine levels

A

Increase

60
Q

How to calculate ANC

A

ANC = WBC * (Segs+Bands) x 1000

61
Q

REMs APS

Double Check

A

Olanzapine
Clozapine

62
Q

Class FGA AEs

A

EPS
QTc
Prolactin
Derm
Photosensitive
Blue gray
Orthostasis
Thermo-regu.

BBB = dementia

63
Q

Class SGA AEs

A

Metabolic
QTc
Blood dyscrasia
Seizure
Anti cholinergic
Sedation
Prolactin
Ophthalmic

64
Q

FDA approved FGA for acute psychosis

A

Chlorpromazine, Haloperidol

65
Q

FDA approved FGA for BPD

A

Loxapine

66
Q

FDA approved FGA for anxiety

A

Trifluoperzine

67
Q

FDA approved FGA for Tourette’s

A

Haloperidol

68
Q

FDA approved SGA for bipolar

A

Aripirazole
Asenapine
Cariprazine
Lumateperone
Lurasidone
Olanzapine
Olanzapine + samidorphan
Quetiapine
Risperidone
Ziprasidone

69
Q

FDA approved SGA for MDD augmentation

A

Aripiprazole

70
Q

FDA approved SGA for autism

A

Aripiprazole
Risperidone

71
Q

FDA approved SGA for tourette’s

A

Aripiprazole

72
Q

FDA approved SGA for MDD

A

Brexpiprazole
Olanzapine
Quetiapine

73
Q

FDA approved SGA for parkinson’s disease psychosis

A

Pimavanserin

74
Q

Can elderly patients with dementia get APS for treatment?

A

Yes if getting treated for schizophrenia. No for pure dementia treatment

PHM 701 (7 decks)

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