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PHM 701 > Final > Flashcards

Final Flashcards

1
Q

PK of alcohol

A

Vd less in men because have decreased lean body mass, gastric emptying = faster absorption, capacity limited metabolism, women has less efficient alcohol dehydrogenase

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2
Q

BAC when need help walking

A

0.25

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3
Q

Epilepsy medications not for breast feeding

A

Ethosuximide and other z one

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4
Q

SJS AEs of AEDs in

A

Lamotrigine, oxcarbamazepine, phenytoin

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5
Q

Weight gain AEs of AED in

A

Gabapentin, keppra

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6
Q

How long before you can give naltrexone

A

7-10 days in withdraw

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7
Q

Creatine normalized drug =

A

urine drug / urine creatine x 100

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8
Q

SGAs AEs of DRESS

A

Olanzapine, Ziprasadone

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9
Q

SGAs AEs of gynecomastia/prolactin

A

Risperidone and Paliperidone

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10
Q

AEs of EPS

A

Risperidone, Paliperidone and FGAs

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11
Q

Metabolic AEs of SGAs

A

Clozapine and Olanzapine

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12
Q

High potency FGAs mean

A

high EPS, low anti cholinergic

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13
Q

Short acting injectables FGA

A

Chloro, Halo, Flu

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14
Q

Long acting injectables FGA

A

Halo, Flu

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15
Q

Short acting injectables SGA

A

Olanzap, Zipras

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16
Q

Long acting injectables SGA

A

Olanza, Arirpi, Risp, Paliper

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17
Q

Avoid what AD in seizure

A

Bupropion

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18
Q

Avoid what AD in substance abuse

A

Benzo

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19
Q

Avoid what AD in cardio

A

TCA’s

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20
Q

Avoid what AD in GI bleeding

A

SSRI

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21
Q

Avoid what AD in anticoagulation

A

SSRI

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22
Q

Beer’s list ADs

A

Bupropion, SSRI, TCA’s

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23
Q

Kids can get what AD

A

Fluoxetine and escitalopram

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24
Q

GAD 1st line

A

EPS DVP

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25
Q

GAD FDA

A

EP DV

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26
Q

SAD 1st line

A

EFPSVP (every few people sad, very purple)

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27
Q

SAD FDA

A

PSV

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28
Q

Panic 1st line

A

SSRI + V

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29
Q

Panic FDA

A

FPSV (for panic syndrome view)

30
Q

PTSD 1st line

A

FPSV (for post syndrome violence)

31
Q

PTSD FDA

32
Q

OCD 1st line

A

SSRI + Clomipramine

33
Q

OCD FDA

34
Q

Benzos for liver

A

Over the liver

35
Q

Hallmark parkinsons

A

loss of dopamine, lewy bodies

36
Q

Sinemet

A

Carbi/Levo

37
Q

Stavelo

A

Carbi/Levo/Enca

38
Q

Off, no on

A

empty, ODT, APO

39
Q

Wearing off

A

inc freq, switch to CR, add MAOi/COMT

40
Q

Delayed onset

A

empty, add IR

41
Q

Peak effect dyskinesia

A

dec. dose, add amantidine, switch to CR, add dopamine agonist

42
Q

Dementia hallmark

A

beta amyloid plaques, neurofibrillary tangles

43
Q

Drugs to treat dementia

A

Donepezil, Rivastigmine, Galantamine, Mementine

44
Q

SQ MS drugs

A

Interferon, Glatiramer, Ofatunumab

45
Q

Infusion MS drugs

A

Mitoxantrone, Natalizumab, Alemtuzumab, Ocrelizumab

46
Q

Oral MS drugs

A

Mavenclad, Fingolimod, Mayzent, Ozonimod, Terifluonomide, Dimethyl fumarate, Diromel fumerate, Monomethyl fumerate

47
Q

First dose monitoring MS

A

Mayzent and Fingolimod

48
Q

PPMS treat with

49
Q

PRMS treat with

A

Mitoxantrone

50
Q

Acute Migraine treatment

A

NSAID, APAP
Triptans
DHE
Rimegepant
Ubrogepant
Lasmiditan
Ergotamine
Fiorcet/Fiornal

51
Q

Migraine Prevention

A

Rimegepant
Atogepant
Topiramate
VPA
Beta blockers
TCAs
Venlafaxine
Vyepti
Aimovig
Emgality
Ajovy
Magnesium
Vitamin b12
Feverfew
Butterbur
Botox

52
Q

Acute tension HA

A

NSAIDs, APAP
Fioricet
Fiorinal

53
Q

Tension preventive

A

TCA
Mirtazapine
Venalfaxine
Gabapentin
Topiramate

54
Q

Acute Cluster

A

DHE
Oxygen
SQ suma
Nasal suma
Nasal zolmitriptan

55
Q

Cluster preventative

A

Verapamil
Glucocorticoids
Galcanezumab
Lithium
Topiramate

56
Q

Menstrual Migraine

A

Frovatriptan
Naratriptan
Zolmitriptan
Estrogen

57
Q

Hemicrania continua

A

Indomethacin

58
Q

HA red flags

A

Systemic infection
Systemic signs
Onset rapid
Onset over 40
Pattern change

59
Q

Sleep onset treat with

A

Ramelteon
BZRAs, DORAs
Melatonin
OTC

Estazolam
Zaleplon
Zolpidem
Suvorexant
Lemborexant
Daridorexant

60
Q

Sleep maintanence treat with

A

Doxepin
Gabapentin
DORA, BZRAs
OTC

Estazolam
Eszopiclone
Zolpidem
TRazodone
Suvorexant
Lemborexant
Daridorexant

61
Q

Eszopiclone brand is

62
Q

Zaleplon brand is

63
Q

RLS treatment

A

Carbi/Levo
Z drugs
opioids

64
Q

Chronic RLS

A

Pregabalin
Gabapentin
Pramipexole
Ropinirole
Rotigotine

65
Q

Pregnancy sleep

A

D,D,D
Doxepin, Doxyalamine, diphenhydramine

66
Q

Prodrugs stroke

A

Plavix, prasugrel

67
Q

Plavix need to switch off

A

CCB, PPI, Statin, Glyburide, Ambien, darifenancin

68
Q

NSAID can cause _

A

ASA resistance

69
Q

If ASA resistance

A

inc. dose, remove interacting, take chew tablet or alka selzter

70
Q

C/I in diperamidolee

A

IBS, migraine, spastic colon

PHM 701 (7 decks)

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