Schizophrenia

Question 1

Describe the auditory hallucinations experienced by schizophrenic patients

Answer 1

3rd person

Question 2

What is meant by positive symptoms and negative symptoms?

Answer 2

Positive are additional symptoms that wouldn’t normally be experienced

Negative is equivalent to apathetic feelings

Question 3

What is the drug pathway involved?

Answer 3

2nd generation anti-psychotic for 6-8weeks
->
1st or 2nd generation 6-8wks
-> 
consider clozapine

Question 4

Name the most commonly used 2nd generation anti-psychotic

Answer 4

Olanzapine

Question 5

What is the most common side effect of 1st generation anti-psychotics?
2nd generation?

Answer 5

1st - EPSE (extra pyramidal side effects e.g. acute dystonic reaction - body seizes up involuntary)

2nd - weight gain and sedation

Question 6

MoA of anti-psychotics

Answer 6

D2 receptor antagonists

D2 = dopamine

Question 7

How common is schizophrenia?

Answer 7

1 in 100

Question 8

How may a patients speech be affected?

Answer 8

Disorganised (complete random words with no sense)

Question 9

What drug is associated with drug induced Parkinsonism?

Answer 9

1st gen anti-psychotics