Sarcoidosis

Question 1

SARCOIDOSIS

1. What is it?
2. What are some features?
3. In what patients is it classically seen in?
4. What are some investigations?
5. What is the management?

Answer 1

1. A multisystem disorder of non-caseating granulomas
2. Erythema nodosum, lupus pernio, hypercalcaemia, arthralgia, bilateral hilar lymphadenopathy, cough, liver, renal and cardiac involvement
3. Young african woman
4. Elevated serum ACE, Hypercalcaemia, elevated ESR & CRP, CXR showing bilateral hilar lymphadenopathy, tissue biopsy showing granulomas, spirometry = restrictive pattern, LFTs for liver involvement, ECG / Echo for cardiac involvement, urine dip for renal involvement
5. None usually, unless HyperCa2+ or eye / heart / lung involvement then steroids