Sarcoidosis

Question 1

What is Sarcoidosis?

Answer 1

• Abnormal collections of inflammatory cells forming granulomas.
• Usually begins in the lungs, skin or lymph nodes.
• Findings that make Sarcoidosis likely are… enlarged lymph nodes at the root of the lung on both sides, high blood calcium with a normal PTH level, or elevated levels of ACE in the blood.
• Exclude TB which presents similar symptoms .

Question 2

What is Lofgren Syndrome?

Answer 2

It’s an acute form of Sarcoidosis characterised by the traid of:

1. Erythema nodosum
2. Bilateral hilar lymphadenopathy
3. Arthralgia

Question 3

In what group of people is Sarcoidosis more common?

Answer 3

Scandinavians, Women, 20-50.

Question 4

What are some common symptoms of Sarcoidosis?

Answer 4

Fatigue, weight loss, arthralgia, arthritis, dry eyes, knee swelling, blurry vision, shortness of breath, a dry hacking cough, skin lesions.

Question 5

What are some cutaneous symptoms of Sarcoidosis?

Answer 5

1. Erythema Nodosum
2. Noduli (small bumps)
3. Granuloma annulare
4. Lupus pernio (chronic raised indurated lesions on face)

Question 6

What is the most common cardiac abnormality associated with Sarcoidosis?

Answer 6

Conduction abnormality (resulting in heart block)

Question 7

What is the most common occular manifestation of Sarcoidosis?

Answer 7

Uveitis

Question 8

What is Heerfordt Syndrome?

Answer 8

It’s a rare form of Sarcoidosis which includes:

• Uveitis
• Parotid gland swelling
• Chronic fever
• Palsy of facial nerves

Question 9

What is the most common neurosarcoidosis sign?

Answer 9

Peripheral facial nerve palsy often bilateral

Question 10

What is the most common blood anomaly indicative of Sarcoidosis?

Answer 10

Lymphopenia