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Module 3 > SAQ: Discuss aspirin resistance > Flashcards

SAQ: Discuss aspirin resistance Flashcards

1
Q

Drug mechanisms

A
  • Some drugs may compete for COX1 binding (NSAIDs)

- PPIs may encourage hydrolysis of aspirin by GI mucosal esterases (not proven)

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2
Q

Possible mutations

A
  • COX-1 polymorphism (not proven)

- GPIIIa platelet receptor

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3
Q

Glucose control and body weight

A
  • Associated with obesity

- high HbA1c

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4
Q

Conditions of high platelet turnover

A
  • CABG
  • ACS
  • Acute/chronic infection/inflammation
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Module 3 (16 decks)

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