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Module 3 > Niacin > Flashcards

Niacin Flashcards

1
Q

What is Niacin

A
  • Nicotinic acid

- Part of Vitamin B3 complex (with nicotinamide)

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2
Q

MOA

A
  • Inhibits formation of triglycerides in the liver
  • Enhances degradation of apolipoprotein B (ApoB) containing lipoproteins (VLDL, LDL)
  • Increase ApoA/I containing lipoproteins (HDL)
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3
Q

How it inhibits TG production

A
  • Direct, non-competetive inhibition of diacylglycerol acyltransferase-2
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Module 3 (16 decks)

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