Santolaya - Population Genetics Flashcards
genetic drift
this would be if we have small small so on a micro level instead of macro. BEcause it is a small family the odds of getting the disease is higher.
founder effect
One person is a big mater and all of his alleles are in the offspring.
bottleneck
populations in history are constricted and then expanded.
Conditional probability
Joint probabilities
Posterior Probabilities
cp - odds of being a carrier using the information that others are carriers.
jp - conditional x prior
pp - joint / all joints
Hardy-Weinberg Equilibrium Criteria
1) Random mating
2) no changes in population due to migration
3) no fluctuations in allele frequency due to natural selection, genetic drift, founder effect, bottleneck, inbreeding
4) no positive or negative selection