Sample Questions 2

Question 1

Generally, in a DNA-containing virus infection, the host animal cell supplies all of the following except
A) RNA polymerase.
B) Nucleotides.
C) DNA polymerase.
D) tRNA.
E) None of the above.

Answer 1

C) DNA polymerase.

Question 2

Put the following in the correct order for DNA-virus replication:
1-Maturation;
2-DNA synthesis;
3-Transcription;
4-Translation.

A) 1,2,3,4
B) 2,3,4,1
C) 3,4,1,2
D) 4,1,2,3
E) 4,3,2,1

Answer 2

B) 2,3,4,1

Question 3

A viral species is a group of viruses that
A) Have the same morphology and nucleic acid.
B) Have the same genetic information and ecological niche.
C) Infect the same cells and cause the same disease.
D) Can’t be defined.

Answer 3

B) Have the same genetic information and ecological niche.

Question 4

Viruses that have reverse transcriptase are in the
A) Retroviridae and Picornaviridae.
B) Herpesviridae and Retroviridae.
C) Hepadnaviridae and Retroviridae.
D) Bacteriophage families.
E) Influenzavirus.

Answer 4

C) Hepadnaviridae and Retroviridae.

Question 5

DNA made from an RNA template will be incorporated into the virus capsid of
A) Retroviridae.
B) Herpesviridae.
C) Hepadnaviridae.
D) Bacteriophage families.
E) Influenzavirus.

Answer 5

C) Hepadnaviridae.

Question 6

Which of the following is not true about viruses?
A) Viruses contain DNA or RNA but never both.
B) Viruses contain a protein coat.
C) Viruses use the anabolic machinery of the cell.
D) Viruses use their own catabolic enzymes.
E) None of the above.

Answer 6

D) Viruses use their own catabolic enzymes.

Question 7

Some viruses, such as Human Herpes Virus 1, infect a cell without causing symptoms; these are called
A) Latent viruses.
B) Lytic viruses.
C) Phages.
D) Slow viruses.
E) Unconventional viruses.

Answer 7

A) Latent viruses.

Question 8

Latent viruses are present in cells as
A) Capsids.
B) Enzymes.
C) Prophages.
D) Proviruses.
E) None of the above.

Answer 8

D) Proviruses.

Question 9

Which one of the following steps does not occur during multiplication of a Rhabdovirus?
A) Synthesis of (+) strands of RNA
B) Synthesis of (-) strands of RNA
C) Synthesis of viral proteins
D) Synthesis of DNA

Answer 9

D) Synthesis of DNA

Question 10

Nontoxic strains of Vibrio cholerae can become toxic when they are in the human intestine with toxic strains of bacteria. This suggests that the toxin genes are acquired by
A) Host enzymes.
B) Prions.
C) Reverse transcriptase.
D) Transduction.
E) None of the above.

Answer 10

D) Transduction.

Question 11

An oncogenic RNA virus must have which of the following enzymes?
A) DNA-dependent DNA polymerase
B) Lysozyme
C) RNA polymerase
D) Reverse transcriptase
E) All of the above

Answer 11

D) Reverse transcriptase

Question 12

Which of the following is most likely a product of an early gene?
A) Capsid proteins
B) DNA polymerase
C) Envelope proteins
D) Spike proteins
E) Lysozyme

Answer 12

B) DNA polymerase

Question 13

Most RNA viruses carry which of the following enzymes?
A) DNA-dependent DNA polymerase
B) Lysozyme
C) RNA-dependent RNA polymerase
D) Reverse transcriptase
E) ATP synthase

Answer 13

C) RNA-dependent RNA polymerase

Question 14

Most prokaryotic cellular reproduction is the result of
A. Conjugation.
B. Binary fission.
C. Meiosis.
D. Mitosis.

Answer 14

B. Binary fission.

Question 15

As prokaryotes divide, a wall is formed. This wall is known as a(n)
A. Septum.
B. Internal membrane.
C. DNA fragment.
D. Plasmid.

Answer 15

A. Septum.

Question 16

“Extra-chromosomal DNA” would best describe
A. Viruses.
B. Prions.
C. Plasmids.
D. Mitochondria.

Answer 16

C. Plasmids.

Question 17

The mature virus particle together with its envelope (if it possesses one) is called the
A. Virus.
B. Capsid.
C. Virion.
D. Nucleocapsid.

Answer 17

C. Virion.

Question 18

The concept of a virus was first developed in the 19th century by
A. D. Ivanowsky
B. R. Koch
C. P. Rous
D. M.W. Beijerinck

Answer 18

D. M.W. Beijerinck

Question 19

The _____ is the protein coat of the virus; the _____ lacks this protein coat.
A. Capsid / virion
B. Capsomere / viroid
C. Capsid / viroid
D. Capsomere / virion

Answer 19

C. Capsid / viroid

Question 20

The typical animal virus has
A. Icosahedral geometry.
B. An axis of 5-fold symmetry.
C. Commonly 60 units per particle.
D. All of the above.

Answer 20

D. All of the above.

Question 21

Which of the following does not apply to enveloped viruses?
A. The membrane lipids are host derived.
B. The glycoproteins of the virus membrane are host encoded.
C. The membrane functions in host penetration.
D. The membrane plays a role in viral infection specificity.

Answer 21

B. The glycoproteins of the virus membrane are host encoded.

Question 22

Single stranded RNA viruses may form mRNA in a host cell by
A. Directs copying (i.e., virus was -RNA)
B. RNA replicase.
C. Reverse transcriptase.
D. Any of the above.

Answer 22

D. Any of the above.

Question 23

Commonly, virus capsids have a regular symmetry. This trait is due to
A. The repetitive pattern of morphological units made up of a few specific proteins.
B. A complex architectural design based on a large number of different
proteins.
C. The mineral or crystalline nature of the virus particle.
D. The protective reaction of the host cell which encases it.

Answer 23

A. The repetitive pattern of morphological units made up of a few specific proteins.

Question 24

In the polio virus, the viral +RNA
A. Acts directly as mRNA.
B. Forms ±DNA which activates a reverse transcriptase.
C. Forms ±RNA.
D. Activates a reverse transcriptase directly (without ±DNA
involvement ).

Answer 24

A. Acts directly as mRNA.

Question 25

Which of the following is not a major animal virus category?
A. ss DNA nonenveloped viruses
B. ds DNA nonenveloped viruses
C. ds DNA enveloped viruses
D. ds RNA enveloped viruses

Answer 25

D. ds RNA enveloped viruses

Question 26

A bacteriophage is a
A. Bacterium that infects viruses.
B. Virus that infects bacteria.
C. Viral antibody that lyses bacteria.
D. Bacterial antibody that lyses viruses.

Answer 26

B. Virus that infects bacteria.

Question 27

The eclipse period of a viral replication cycle is the period
A. Prior to infection of the host cell.
B. After infection of the host cell but prior to maturation.
C. Immediately following the maturation period.
D. Immediately after the virions are released from the host.

Answer 27

B. After infection of the host cell but prior to maturation.

Question 28

The latent period of a viral infection is the
A. Eclipse period.
B. Adsorption period.
C. Eclipse period plus the adsorption period.
D. Lytic period.

Answer 28

C. Eclipse period plus the adsorption period.

Question 29

Which of the following virus types would be associated with cell
transformation in animals?
A. Pox viruses
B. Picornaviruses
C. Retroviruses
D. Reoviruses

Answer 29

C. Retroviruses

Question 30

Which of the following is/are true about RNA viruses?
A. The nucleic acid (RNA) is always in linear form.
B. The RNA of some viruses is fragmented into several molecules.
C. The RNA of some viruses has linked polypeptides.
D. All of the above.

Answer 30

D. All of the above.

Question 31

Which of the following could function as viral receptors on a host cell?
As Pitior flagella
B. Transport binding proteins
C. Glycoproteins
D. Any of the above

Answer 31

D. Any of the above

Question 32

In cells carrying the lambda phage, the only gene which is expressed
continuously produces the
A. Repressor protein.
B. Inducer protein.
C. Corepressor protein,
D. Transcription protein.

Answer 32

A. Repressor protein.