Salmonella Typhi

Question 0

Causative agent

Answer 0

Salmonella serotype Typhi (typhoid fever) and Salmonella serotype Paratyphi (paratyphi fever) gram negative member of enterobacteriaceae

Question 1

Signs and symptoms

Answer 1

Fever, headache, constipation, abdominal pain, intestinal rupture, internal bleeding, shock and even death.

Question 2

Pathogenesis

Answer 2

Cross the intestinal epithelium via M cells; taken up by macrophages and multiplying within. Carried to the bloodstream in the body. The Peyer’s patch are sometimes destroyed=ruptured intestines and hemorrhage

Question 3

Epidemiology

Answer 3

Humans only source of infection, person to person fecal oral transmission

Question 4

Treatments

Answer 4

Antibiotics. Attenuated and inactivated vaccines for typhoid fever; no vaccine for paratyphoid fever

Question 5

Define Typhoid and Paratyphoid fever

Answer 5

Enteric fever, systemic diseases in intestines