Clostridium Difficile Flashcards
0
Q
Pathogenesis
A
Toxins disrupt host cell actin, causing Lethal effects to intestinal epithelium
1
Q
Causative agent
A
Clostridium difficile, gram positive rod shape anaerobe endospore
2
Q
Signs n symptoms
A
Fever, diarrhea due to pseudo membranous colitis (inflammation of colon), fatal inflammation of colon
3
Q
Epidemiology
A
Primarily occurs in hospitalized patients on antibiotic therapy
4
Q
Treatment and prevention
A
When feasible, stop antibiotics, vancomycin, metrodazole, difficid
6
Q
Hyper virulent stain
A
More toxins than regular toxins, more resistant to antibiotics, outbreaks
